original papers 英文原著論文

2017

Takagishi M, Sawada M, Ohata S, Asai N, Enomoto A, Takahashi K, Weng L, Ushida K, Ara H, Matsui S, Kaibuchi K, Sawamoto K, Takahashi M (2017) Daple coordinates planar polarized microtubule dynamics in ependymal cells and contributes to hydrocephalus. Cell Rep 20(4), 960–972. https://doi.org/10.1016/j.celrep.2017.06.089

Cebrián-Silla A, Alfaro-Cervelló C, Herranz-Pérez V, Kaneko N, Park DH, Sawamoto K, Alvarez-Buylla A, Lim DA, García-Verdugo JM (2017) Unique organization of the nuclear envelope in the post-natal quiescent neural stem cells. Stem Cell Reports pii: S2213-6711(17)30231-X. doi: 10.1016/j.stemcr.2017.05.024.

Oshikawa M, Okada K, Kaneko N, Sawamoto K, Ajioka I (2017)  Angiogenic biomaterials for brain ischemia using affinity-immobilized VEGF on laminin porous sponge. Adv Healthcare Mater 2017: 1700183. doi: 10.1002/adhm.201700183

Fujioka T, Kaneko N, Ajioka I, Nakaguchi K, Omata T, Ohba H, Fässler R, García-Verdugo JM, Sekiguchi K, Matsukawa N, Sawamoto K (2017) β1 integrin signaling promotes neuronal migration along vascular scaffolds in the post-stroke brain. EBioMedicine 16:195-203 doi: 10.1016/j.ebiom.2017.01.005. FREE Full text

2016

Matsunami K, Nishida N, Kaneko N, Ikeo K, Toyo-Oka L, Takeuchi H, Matsuura K, Tamori A, Nomura H, Yoshiji H, Imamura M, Masaki N, Hayakawa T, Ide T, Shimada N, Ikeda F, Hino K, Nishiguchi S, Okuse C, Nojiri S, Sawamoto K, Tokunaga K, Joh T, Tanaka Y (2016) Genome-Wide Association Study Identifies ZNF354C Variants Associated with Depression from Interferon-Based Therapy for Chronic Hepatitis C. PLoS One 11(10):e0164418. doi: 10.1371/journal.pone.0164418

Miyake M, Ito Y, Sawada M, Sakai K, Suzuki H, Sakamoto T, Sawamoto K, Kamijima M (2016) Subchronic inhalation exposure to 2-ethyl-1-hexanol impairs the mouse olfactory bulb via injury and subsequent repair of the nasal olfactory epithelium. Arch Toxicol 90: 1949-1958Pubmed

Ogino T, Sawada M, Takase H, Nakai C, Herranz-Pérez V, Cebrián-Silla A, Kaneko N, Manuel García-Verdugo J, Sawamoto K (2016) Characterization of multiciliated ependymal cells that emerge in the neurogenic niche of the aged zebrafish brain. J Comp Neurol 524: 2982-2992. Pubmed

Hirota Y, Sawada M, Huang SH, Ogino T, Ohata S, Kubo A and Sawamoto K (2016) Roles of Wnt signaling in the neurogenic niche of the adult mouse ventricular-subventricular zone. Neurochem Res 41:222-230. Pubmed

2015

Yamagishi S, Yamada K, Sawada M, Nakano S, Mori N, Sawamoto K and Sato K (2015) Netrin-5 is highly expressed in neurogenic regions of the adult brain. Front Cell Neurosci 9:146. doi: 10.3389/fncel.2015.00146

Zheng LS, Kaneko N and Sawamoto K (2015) Minocycline treatment ameliorates interferon-alpha-induced neurogenic defects and depression-like behaviors in mice. Front Cell Neurosci 9:5. doi: 10.3389/fncel.2015.00005

Ajioka I, Jinnou H, Okada K, Sawada M, Saitoh S, Sawamoto K (2015) Enhancement of neuroblast migration into the injured cerebral cortex using laminin-containing porous sponge. Tissue Eng Part A 21: 193-201. (Online instant publication of accepted manuscript)

2014

Ota H, Hikita T, Sawada M, Nishioka T, Matsumoto M, Komura M, Ohno A, Kamiya Y, Miyamoto T, Asai N, Enomoto A, Takahashi M, Kaibuchi K, Sobue K, Sawamoto K (2014) Speed control for neuronal migration in the postnatal brain by Gmip-mediated local inactivation of RhoA. Nat Commun 5: 4532. DOI: 10.1038/ncomms5532 Pubmed

Zheng LS, Hitoshi S, Kaneko N, Takao K, Miyakawa T, Tanaka Y, Xia H, Kalinke U, Kudo K, Kanba S, Ikenaka K, Sawamoto K (2014) Mechanisms for interferon-alpha-induced depression and neural stem cell dysfunction. Stem Cell Rep 3: 73-84.?DOI: http://dx.doi.org/10.1016/j.stemcr.2014.05.015 Pubmed

Hikita T, Ohno A, Sawada M, Ota H, Sawamoto K (2014) Rac1-mediated indentation of resting neurons promotes the chain migration of new neurons in the rostral migratory stream of postnatal mouse brain. J Neurochem 128: 790-797. DOI: 10.1111/jnc.12518 Pubmed

2013

Ota H, Hikita T, Nishioka T, Matsumoto M, Ito J, Asai N, Enomoto A, Takahashi M, Kaibuchi K, Sobue K, Sawamoto K (2013) Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain. Biochem Biophys Res Commun 442: 16-21. Pubmed

Kishimoto N, Asakawa K, Madelaine R, Blader P, Kawakami K, Sawamoto K (2013) Interhemispheric asymmetry of olfactory input-dependent neuronal specification in the adult brain. Nat Neurosci 16: 884-888. Pubmed

Yamagata M, Yamamoto A, Kako E, Kaneko N, Matsubara K, Sakai K, Sawamoto K, Ueda M (2013) Human dental pulp-derived stem cells protect against hypoxic-ischemic brain injury in neonatal mice. Stroke 44: 551-554. Pubmed

2012

Kato Y, Kaneko N, Sawada M, Ito K, Arakawa S, Murakami S, Sawamoto K (2012) A subtype-specific critical period for neurogenesis in the postnatal development of mouse olfactory glomeruli. PLoS ONE 7 (11): e48431. doi: 10.1371/journal.pone.0048431. FREE Full text 

Nakaguchi K, Jinnou H, Kaneko N, Sawada M, Hikita T, Saitoh S, Tabata Y, Sawamoto K (2012) Growth factors released from gelatin hydrogel microspheres increase new neurons in the adult mouse brain. Stem Cells Int 2012, Article ID 915160, 7 pages, doi: 10.1155/2012/915160. FREE Full Text

Kako E, Kaneko N, Aoyama M, Hida H, Takebayashi H, Ikenaka K, Asai K, Togari H, Sobue K, Sawamoto K (2012) Subventricular-zone derived oligodendrogenesis in injured neonatal white-matter in mice enhanced by a nonerythropoietic EPO derivative. Stem Cells 30: 2234-2247. 名市大研究トピックス Pubmed

Hirota Y, Sawada M, Kida YS, Huang S, Yamada O, Sakaguchi M, Ogura T, Okano H, Sawamoto K (2012) Roles of planar cell polarity signaling in maturation of neuronal precursor cells in the postnatal mouse olfactory bulb. Stem Cells 30: 1726-1733. Pubmed

Suyama S, Sunabori T, Kanki H, Sawamoto K, Gachet C, Koizumi S, Okano H (2012) Purinergic signaling promotes proliferation of adult mouse subventricular zone cells. J Neurosci 32: 9238-9247.

Kishimoto N, Shimizu K, Sawamoto, K (2012) Neuronal regeneration in a zebrafish model of adult brain injury. Dis Models Mech 5: 200-209. FREE full text

Shinohara R, Thumkeo D, Kamijo H, Kaneko N, Sawamoto K, Watanabe K, Takebayashi H, Kiyonari H, Ishizaki T, Furuyashiki T, Narumia S (2012) A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors. Nat Neurosci 15: 373-380.

2011

Sawada M, Kaneko N, Inada H, Wake H, Kato Y, Yanagawa Y, Kobayashi K, Nemoto T, Nabekura J, Sawamoto K (2011) Sensory input regulates spatial and subtype-specific patterns of neuronal turnover in the adult olfactory bulb. J Neurosci31:11587-11596. 名市大研究トピックス FREE Full text

Kishimoto N, Alfaro-Cervello C, Shimizu K, Asakawa K, Urasaki A, Nonaka S, Kawakami K, Garcia-Verdugo JM, Sawamoto K (2011) Migration of neuronal precursors from the telencephalic ventricular zone into the olfactory bulb in adult zebrafish. J Comp Neurol 519:3549-3565. Pubmed

Wang Y, Kaneko N, Asai N, Enomoto A, Isotani-Sakakibara M, Kato T, Asai M, Murakumo Y, Ota H, Hikita T, Namba T, Kuroda K, Kaibuchi K, Ming GL, Song H, Sawamoto K, Takahashi M (2011) Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain. J Neurosci 31:8109-8122. FREE Full text

Sawamoto K, Hirota Y, Alfaro-Cervello C, Soriano-Navarro M, He X, Hayakawa-Yano Y, Yamada M, Hikishima K, Tabata H, Iwanami A, Nakajima K, Toyama Y, Itoh T, Alvarez-Buylla A, Garcia-Verdugo JM, Okano H (2011) Cellular composition and organization of the subventricular zone and rostral migratory stream in the adult and neonatal common marmoset brain. J Comp Neurol 519:690-713. Pubmed

Kato S, Aoyama M, Kakita H, Hida H, Kato I, Ito T, Goto T, Hussein MH, Sawamoto K, Togari H, Asai K (2011) Endogenous erythropoietin from astrocyte protects the oligodendrocyte precursor cell against hypoxic and reoxygenation injury. J Neurosci Res 89:1566-1574.

Yamane J, Ishibashi S, Sakaguchi M, Kuroiwa T, Kanemura Y, Nakamura M, Miyoshi H, Sawamoto K, Toyama Y, Mizusawa H, Okano H (2011) Transplantation of human neural stem/progenitor cells overexpressing Galectin-1 improves functional recovery from focal brain ischemia in the Mongolian gerbil. Mol Brain 4:35.

Imaizumi Y, Sakaguchi M, Morishita T, Ito M, Poirier F, Sawamoto K, Okano H (2011) Galectin-1 is expressed in early-type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus. Mol Brain 4:7.

Shimada M, Haruta M, Niida H, Sawamoto K, Nakanishi M (2010) Protein phosphatase 1gamma is responsible fordephosphorylation of histone H3 at Thr 11 after DNA damage. EMBO Rep 11:883-889.

Sakaguchi M, Imaizumi Y, Shingo T, Tada H, Hayama K, Yamada O, Morishita T, Kadoya T, Uchiyama N, Shimazaki T, Kuno A, Poirier F, Hirabayashi J, Sawamoto K, Okano H (2010) Regulation of adult neural progenitor cells by Galectin-1/beta1 Integrin interaction. J Neurochem 113:1516-1524.

2010

Oki K, Kaneko N, Kanki H, Imai T, Suzuki N, Sawamoto K, Okano H (2010) Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia. Neurosci Res 66:390-395.Pubmed

Kojima T, Hirota Y, Ema M, Takahashi S, Miyoshi I, Okano H, Sawamoto K (2010) Subventricular zone-derived neural progenitor cells migrate along a blood vessel scaffold toward the post-stroke striatum. Stem Cells 28:545-554.FREE Full text

Kaneko N, Marin O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K (2010) New Neurons Clear the Path of Astrocytic Processes for Their Rapid Migration in the Adult Brain. Neuron 67:213-223. ライフサイエンス新着論文レビュー 名市大研究トピックスPubmed

Ikeda M, Hirota Y, Sakaguchi M, Yamada O, Kida YS, Ogura T, Otsuka T, Okano H, Sawamoto K (2010) Expression and Proliferation-Promoting Role of Diversin in the Neuronally Committed Precursor Cells Migrating in the Adult Mouse Brain. Stem Cells 28:2017-2026. 名市大研究トピックスFREE Full Text

Hirota Y, Meunier A, Huang S, Shimozawa T, Yamada O, Kida YS, Inoue M, Ito T, Kato H, Sakaguchi M, Sunabori T, Nakaya MA, Nonaka S, Ogura T, Higuchi H, Okano H, Spassky N, Sawamoto K (2010) Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II. Development 137:3037-3046.名市大研究トピックスFREE Full text

Guirao B, Meunier A, Mortaud S, Aguilar A, Corsi JM, Strehl L, Hirota Y, Desoeuvre A, Boutin C, Han YG, Mirzadeh Z, Cremer H, Montcouquiol M, Sawamoto K, Spassky N (2010) Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia. Nat Cell Biol 12:341-350.Pubmed

Mirzadeh Z, Doetsch F, Sawamoto K, Wichterle H, Alvarez-Buylla A (2010) The subventricular zone en-face: wholemount staining and ependymal flow. J Vis Exp:http://www.jove.com/index/details.stp id=1938, doi: 1910.3791/1938.

2009

Tamase A, Muraguchi T, Naka K, Tanaka S, Kinoshita M, Hoshii T, Ohmura M, Shugo H, Ooshio T, Nakada M, Sawamoto K, Onodera M, Matsumoto K, Oshima M, Asano M, Saya H, Okano H, Suda T, Hamada J, Hirao A (2009) Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin. Proc Natl Acad Sci U S A 106:17163-17168.

Suzuki T, Miyamoto H, Nakahari T, Inoue I, Suemoto T, Jiang B, Hirota Y, Itohara S, Saido TC, Tsumoto T, Sawamoto K, Hensch TK, Delgado-Escueta AV, Yamakawa K (2009) Efhc1 deficiency causes spontaneous myoclonus and increased seizure susceptibility. Hum Mol Genet 18:1099-1109.

Enomoto A, Asai N, Namba T, Wang Y, Kato T, Tanaka M, Tatsumi H, Taya S, Tsuboi D, Kuroda K, Kaneko N, Sawamoto K, Miyamoto R, Jijiwa M, Murakumo Y, Sokabe M, Seki T, Kaibuchi K, Takahashi M (2009) Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron 63:774-787.

2008

Sunabori T, Tokunaga A, Nagai T, Sawamoto K, Okabe M, Miyawaki A, Matsuzaki Y, Miyata T, Okano H (2008) Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors. J Cell Sci 121:1204-1212.

Kohyama J, Kojima T, Takatsuka E, Yamashita T, Namiki J, Hsieh J, Gage FH, Namihira M, Okano H, Sawamoto K, Nakashima K (2008) Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. Proc Natl Acad Sci U S A 105:18012-18017.

2007

Hirota Y, Ohshima T, Kaneko N, Ikeda M, Iwasato T, Kulkarni AB, Mikoshiba K, Okano H, Sawamoto K (2007) Cyclin-dependent kinase 5 is required for control of neuroblast migration in the postnatal subventricular zone. J Neurosci 27:12829-12838.FREE Full text

Adachi K, Mirzadeh Z, Sakaguchi M, Yamashita T, Nikolcheva T, Gotoh Y, Peltz G, Gong L, Kawase T, Alvarez-Buylla A, Okano H, Sawamoto K (2007) Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone. Stem Cells 25:2827-2836.FREE Full text

2006

Sawamoto K, Wichterle H, Gonzalez-Perez O, Cholfin JA, Yamada M, Spassky N, Murcia NS, Garcia-Verdugo JM, Marin O, Rubenstein JL, Tessier-Lavigne M, Okano H, Alvarez-Buylla A (2006) New neurons follow the flow of cerebrospinal fluid in the adult brain. Science 311:629-632.Pubmed

Yamashita T, Ninomiya M, Hernandez Acosta P, Garcia-Verdugo JM, Sunabori T, Sakaguchi M, Adachi K, Kojima T, Hirota Y, Kawase T, Araki N, Abe K, Okano H, Sawamoto K (2006) Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum. J Neurosci 26:6627-6636.FREE Full text

Ninomiya M, Yamashita T, Araki N, Okano H, Sawamoto K (2006) Enhanced neurogenesis in the ischemic striatum following EGF-induced expansion of transit-amplifying cells in the subventricular zone. Neurosci Lett 403:63-67. Pubmed

Kaneko N, Okano H, Sawamoto K (2006) Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb. Genes Cells 11:1145-1159. FREE Full text

Yamashima T, Popivanova BK, Guo J, Kotani S, Wakayama T, Iseki S, Sawamoto K, Okano H, Fujii C, Mukaida N, Tonchev AB (2006) Implication of “Down syndrome cell adhesion molecule” in the hippocampal neurogenesis of ischemic monkeys. Hippocampus 16:924-935.

Toriya M, Tokunaga A, Sawamoto K, Nakao K, Okano H (2006) Distinct functions of human numb isoforms revealed by misexpression in the neural stem cell lineage in the Drosophila larval brain. Dev Neurosci 28:142-155.

Tonchev AB, Yamashima T, Sawamoto K, Okano H (2006) Transcription factor protein expression patterns by neural or neuronal progenitor cells of adult monkey subventricular zone. Neuroscience 139:1355-1367.

Sakaguchi M, Shingo T, Shimazaki T, Okano HJ, Shiwa M, Ishibashi S, Oguro H, Ninomiya M, Kadoya T, Horie H, Shibuya A, Mizusawa H, Poirier F, Nakauchi H, Sawamoto K, Okano H (2006) A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. Proc Natl Acad Sci U S A 103:7112-7117.

Miyagi S, Nishimoto M, Saito T, Ninomiya M, Sawamoto K, Okano H, Muramatsu M, Oguro H, Iwama A, Okuda A (2006) The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon. J Biol Chem 281:13374-13381.

2005

Yamashita T, Sawamoto K, Suzuki S, Suzuki N, Adachi K, Kawase T, Mihara M, Ohsugi Y, Abe K, Okano H (2005) Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons. J Neurochem 94:459-468.

Tonchev AB, Yamashima T, Sawamoto K, Okano H (2005) Enhanced proliferation of progenitor cells in the subventricular zone and limited neuronal production in the striatum and neocortex of adult macaque monkeys after global cerebral ischemia. J Neurosci Res 81:776-788.

Suzuki S, Yamashita T, Tanaka K, Hattori H, Sawamoto K, Okano H, Suzuki N (2005) Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats. J Cereb Blood Flow Metab 25:685-693.

Kanuka H, Hiratou T, Igaki T, Kanda H, Kuranaga E, Sawamoto K, Aigaki T, Okano H, Miura M (2005) Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity. Biochim Biophys Acta 1726:225-237.

Hirota Y, Sawamoto K, Takahashi K, Ueda R, Okano H (2005) The transmembrane protein, Tincar, is involved in the development of the compound eye in Drosophila melanogaster. Dev Genes Evol 215:90-96.

2004

Yoshizaki T, Inaji M, Kouike H, Shimazaki T, Sawamoto K, Ando K, Date I, Kobayashi K, Suhara T, Uchiyama Y, Okano H (2004) Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells. Neurosci Lett 363:33-37.

Yamashima T, Tonchev AB, Vachkov IH, Popivanova BK, Seki T, Sawamoto K, Okano H (2004) Vascular adventitia generates neuronal progenitors in the monkey hippocampus after ischemia. Hippocampus 14:861-875.

Unezaki S, Nishizawa M, Okuda-Ashitaka E, Masu Y, Mukai M, Kobayashi S, Sawamoto K, Okano H, Ito S (2004) Characterization of the isoforms of MOVO zinc finger protein, a mouse homologue of Drosophila Ovo, as transcription factors. Gene 336:47-58.

Tokunaga A, Kohyama J, Yoshida T, Nakao K, Sawamoto K, Okano H (2004) Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain. J Neurochem 90:142-154.

2002

Uchida M, Hanai S, Uematsu N, Sawamoto K, Okano H, Miwa M, Uchida K (2002) Overexpression of poly(ADP-ribose) polymerase disrupts organization of cytoskeletal F-actin and tissue polarity in Drosophila. J Biol Chem 277:6696-6702.

Ogawa Y, Sawamoto K, Miyata T, Miyao S, Watanabe M, Nakamura M, Bregman BS, Koike M, Uchiyama Y, Toyama Y, Okano H (2002) Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. J Neurosci Res 69:925-933.

Kuranaga E, Kanuka H, Igaki T, Sawamoto K, Ichijo H, Okano H, Miura M (2002) Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila. Nat Cell Biol 4:705-710.

Hirota Y, Sawamoto K, Okano H (2002) tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila. Mech Dev 119 Suppl 1:S279-283.

2001

Uchida M, Hanai S, Uematsu N, Sawamoto K, Okano H, Miwa M, Uchida K (2001) Genetic and functional analysis of PARP, a DNA strand break-binding enzyme. Mutat Res 477:89-96.

Sawamoto K, Yamamoto A, Kawaguchi A, Yamaguchi M, Mori K, Goldman SA, Okano H (2001) Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent proteins regulated by stage-specific neural promoters. J Neurosci Res 65:220-227.

Sawamoto K, Nakao N, Kobayashi K, Matsushita N, Takahashi H, Kakishita K, Yamamoto A, Yoshizaki T, Terashima T, Murakami F, Itakura T, Okano H (2001) Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proc Natl Acad Sci U S A 98:6423-6428.

Sawamoto K, Nakao N, Kakishita K, Ogawa Y, Toyama Y, Yamamoto A, Yamaguchi M, Mori K, Goldman SA, Itakura T, Okano H (2001) Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. J Neurosci 21:3895-3903.

Kawaguchi A, Miyata T, Sawamoto K, Takashita N, Murayama A, Akamatsu W, Ogawa M, Okabe M, Tano Y, Goldman SA, Okano H (2001) Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells. Mol Cell Neurosci 17:259-273.

2000

Taguchi A, Sawamoto K, Okano H (2000) Mutations modulating the Argos-regulated signaling pathway in Drosophila eye development. Genetics 154:1639-1648.

Tabuchi K, Sawamoto K, Suzuki E, Ozaki K, Sone M, Hama C, Tanifuji-Morimoto T, Yuasa Y, Yoshihara Y, Nose A, Okano H (2000) GAL4/UAS-WGA system as a powerful tool for tracing Drosophila transsynaptic neural pathways. J Neurosci Res 59:94-99.

Kaneko Y, Sakakibara S, Imai T, Suzuki A, Nakamura Y, Sawamoto K, Ogawa Y, Toyama Y, Miyata T, Okano H (2000) Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells. Dev Neurosci 22:139-153.

Jin MH, Sawamoto K, Ito M, Okano H (2000) The interaction between the Drosophila secreted protein argos and the epidermal growth factor receptor inhibits dimerization of the receptor and binding of secreted spitz to the receptor. Mol Cell Biol 20:2098-2107.

Igaki T, Kanuka H, Inohara N, Sawamoto K, Nunez G, Okano H, Miura M (2000) Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death. Proc Natl Acad Sci U S A 97:662-667.

1999

Yoshihara Y, Mizuno T, Nakahira M, Kawasaki M, Watanabe Y, Kagamiyama H, Jishage K, Ueda O, Suzuki H, Tabuchi K, Sawamoto K, Okano H, Noda T, Mori K (1999) A genetic approach to visualization of multisynaptic neural pathways using plant lectin transgene. Neuron 22:33-41.

Sawamoto K, Yamada C, Kishida S, Hirota Y, Taguchi A, Kikuchi A, Okano H (1999) Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development. Oncogene 18:1967-1974.

Sawamoto K, Winge P, Koyama S, Hirota Y, Yamada C, Miyao S, Yoshikawa S, Jin MH, Kikuchi A, Okano H (1999) The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway. J Cell Biol 146:361-372.

Kanuka H, Sawamoto K, Inohara N, Matsuno K, Okano H, Miura M (1999) Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator. Mol Cell 4:757-769.

Kanuka H, Hisahara S, Sawamoto K, Shoji S, Okano H, Miura M (1999) Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: implicated mechanisms for caspase activation. Proc Natl Acad Sci U S A 96:145-150.

Hirota Y, Okabe M, Imai T, Kurusu M, Yamamoto A, Miyao S, Nakamura M, Sawamoto K, Okano H (1999) Musashi and seven in absentia downregulate Tramtrack through distinct mechanisms in Drosophila eye development. Mech Dev 87:93-101.

Fujimoto J, Sawamoto K, Okabe M, Takagi Y, Tezuka T, Yoshikawa S, Ryo H, Okano H, Yamamoto T (1999) Cloning and characterization of Dfak56, a homolog of focal adhesion kinase, in Drosophila melanogaster. J Biol Chem 274:29196-29201.

1998

Tabuchi K, Yoshikawa S, Yuasa Y, Sawamoto K, Okano H (1998) A novel Drosophila paired-like homeobox gene related to Caenorhabditis elegans unc-4 is expressed in subsets of postmitotic neurons and epidermal cells. Neurosci Lett 257:49-52.

Sawamoto K, Taguchi A, Hirota Y, Yamada C, Jin MH, Okano H (1998) Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway. Cell Death Differ 5:262-270.

Saito T, Sawamoto K, Okano H, Anderson DJ, Mikoshiba K (1998) Mammalian BarH homologue is a potential regulator of neural bHLH genes. Dev Biol 199:216-225.

1997

Sawamoto K, Takahashi N (1997) Modulation of hepatocyte function by changing the cell shape in primary culture. In Vitro Cell Dev Biol Anim 33:569-574.

1996

Sawamoto K, Okabe M, Tanimura T, Mikoshiba K, Nishida Y, Okano H (1996) The Drosophila secreted protein Argos regulates signal transduction in the Ras/MAPK pathway. Dev Biol 178:13-22.

Sawamoto K, Okabe M, Tanimura T, Hayashi S, Mikoshiba K, Okano H (1996) argos Is required for projection of photoreceptor axons during optic lobe development in Drosophila. Dev Dyn 205:162-171.

Okabe M, Sawamoto K, Okano H (1996) The function of the Drosophila argos gene product in the development of embryonic chordotonal organs. Dev Biol 175:37-49.

1995

Sawamoto K, Takahashi N (1995) Changes in the organelle arrangement in primary cultured hepatocytes following the formation of cytoskeleton. Int J Tissue React 17:205-210.

1994

Sawamoto K, Okano H, Kobayakawa Y, Hayashi S, Mikoshiba K, Tanimura T (1994) The function of argos in regulating cell fate decisions during Drosophila eye and wing vein development. Dev Biol 164:267-276.

Okano H, Yoshikawa S, Suzuki A, Ueno N, Kaizu M, Okabe M, Takahashi T, Matsumoto M, Sawamoto K, Mikoshiba K (1994) Cloning of a Drosophila melanogaster homologue of the mouse type-I bone morphogenetic proteins-2/-4 receptor: a potential decapentaplegic receptor. Gene 148:203-209.

1992

Okano H, Hayashi S, Tanimura T, Sawamoto K, Yoshikawa S, Watanabe J, Iwasaki M, Hirose S, Mikoshiba K, Montell C (1992) Regulation of Drosophila neural development by a putative secreted protein. Differentiation 52:1-11.