1. Guirao, B., Meunier, A., Mortaud, S., Aguilar, A., Corsi, J.M., Strehl, L., Hirota, Y., Desoeuvre, A., Boutin, C., Han, Y.G., Mirzadeh, Z., Cremer, H., Montcouquiol, M., Sawamoto, K., and Spassky, N. (2010) Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia. Nat Cell Biol

2. Kojima, T., Hirota, Y., Ema, M., Takahashi, S., Miyoshi, I., Okano, H., and Sawamoto, K. (2010) Subventricular Zone-Derived Neural Progenitor Cells Migrate Along a Blood Vessel Scaffold Toward the Post-Stroke Striatum. Stem Cells

3. Tamase, A., Muraguchi, T., Naka, K., Tanaka, S., Kinoshita, M., Hoshii, T., Ohmura, M., Shugo, H., Ooshio, T., Nakada, M., Sawamoto, K., Onodera, M., Matsumoto, K., Oshima, M., Asano, M., Saya, H., Okano, H., Suda, T., Hamada, J., and Hirao, A. (2009) Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin. Proc Natl Acad Sci U S A 106, 17163-17168

4. Suzuki, T., Miyamoto, H., Nakahari, T., Inoue, I., Suemoto, T., Jiang, B., Hirota, Y., Itohara, S., Saido, T.C., Tsumoto, T., Sawamoto, K., Hensch, T.K., Delgado-Escueta, A.V., and Yamakawa, K. (2009) Efhc1 deficiency causes spontaneous myoclonus and increased seizure susceptibility. Hum Mol Genet 18, 1099-1109

5. Oki, K., Kaneko, N., Kanki, H., Imai, T., Suzuki, N., Sawamoto, K., and Okano, H. (2009) Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia. Neurosci Res

6. Enomoto, A., Asai, N., Namba, T., Wang, Y., Kato, T., Tanaka, M., Tatsumi, H., Taya, S., Tsuboi, D., Kuroda, K., Kaneko, N., Sawamoto, K., Miyamoto, R., Jijiwa, M., Murakumo, Y., Sokabe, M., Seki, T., Kaibuchi, K., and Takahashi, M. (2009) Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron 63, 774-787

7. Sunabori, T., Tokunaga, A., Nagai, T., Sawamoto, K., Okabe, M., Miyawaki, A., Matsuzaki, Y., Miyata, T., and Okano, H. (2008) Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors. J Cell Sci 121, 1204-1212

8. Kohyama, J., Kojima, T., Takatsuka, E., Yamashita, T., Namiki, J., Hsieh, J., Gage, F.H., Namihira, M., Okano, H., Sawamoto, K., and Nakashima, K. (2008) Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. Proc Natl Acad Sci U S A 105, 18012-18017

9. Hirota, Y., Ohshima, T., Kaneko, N., Ikeda, M., Iwasato, T., Kulkarni, A.B., Mikoshiba, K., Okano, H., and Sawamoto, K. (2007) Cyclin-dependent kinase 5 is required for control of neuroblast migration in the postnatal subventricular zone. J Neurosci 27, 12829-12838

10. Adachi, K., Mirzadeh, Z., Sakaguchi, M., Yamashita, T., Nikolcheva, T., Gotoh, Y., Peltz, G., Gong, L., Kawase, T., Alvarez-Buylla, A., Okano, H., and Sawamoto, K. (2007) Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone. Stem Cells 25, 2827-2836

11. Yamashita, T., Ninomiya, M., Hernandez Acosta, P., Garcia-Verdugo, J.M., Sunabori, T., Sakaguchi, M., Adachi, K., Kojima, T., Hirota, Y., Kawase, T., Araki, N., Abe, K., Okano, H., and Sawamoto, K. (2006) Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum. J Neurosci 26, 6627-6636

12. Yamashima, T., Popivanova, B.K., Guo, J., Kotani, S., Wakayama, T., Iseki, S., Sawamoto, K., Okano, H., Fujii, C., Mukaida, N., and Tonchev, A.B. (2006) Implication of “Down syndrome cell adhesion molecule” in the hippocampal neurogenesis of ischemic monkeys. Hippocampus 16, 924-935

13. Toriya, M., Tokunaga, A., Sawamoto, K., Nakao, K., and Okano, H. (2006) Distinct functions of human numb isoforms revealed by misexpression in the neural stem cell lineage in the Drosophila larval brain. Dev Neurosci 28, 142-155

14. Tonchev, A.B., Yamashima, T., Sawamoto, K., and Okano, H. (2006) Transcription factor protein expression patterns by neural or neuronal progenitor cells of adult monkey subventricular zone. Neuroscience 139, 1355-1367

15. Sawamoto, K., Wichterle, H., Gonzalez-Perez, O., Cholfin, J.A., Yamada, M., Spassky, N., Murcia, N.S., Garcia-Verdugo, J.M., Marin, O., Rubenstein, J.L., Tessier-Lavigne, M., Okano, H., and Alvarez-Buylla, A. (2006) New neurons follow the flow of cerebrospinal fluid in the adult brain. Science 311, 629-632

16. Sakaguchi, M., Shingo, T., Shimazaki, T., Okano, H.J., Shiwa, M., Ishibashi, S., Oguro, H., Ninomiya, M., Kadoya, T., Horie, H., Shibuya, A., Mizusawa, H., Poirier, F., Nakauchi, H., Sawamoto, K., and Okano, H. (2006) A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. Proc Natl Acad Sci U S A 103, 7112-7117

17. Ninomiya, M., Yamashita, T., Araki, N., Okano, H., and Sawamoto, K. (2006) Enhanced neurogenesis in the ischemic striatum following EGF-induced expansion of transit-amplifying cells in the subventricular zone. Neurosci Lett 403, 63-67

18. Miyagi, S., Nishimoto, M., Saito, T., Ninomiya, M., Sawamoto, K., Okano, H., Muramatsu, M., Oguro, H., Iwama, A., and Okuda, A. (2006) The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon. J Biol Chem 281, 13374-13381

19. Kaneko, N., Okano, H., and Sawamoto, K. (2006) Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb. Genes Cells 11, 1145-1159

20. Yamashita, T., Sawamoto, K., Suzuki, S., Suzuki, N., Adachi, K., Kawase, T., Mihara, M., Ohsugi, Y., Abe, K., and Okano, H. (2005) Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons. J Neurochem 94, 459-468

21. Tonchev, A.B., Yamashima, T., Sawamoto, K., and Okano, H. (2005) Enhanced proliferation of progenitor cells in the subventricular zone and limited neuronal production in the striatum and neocortex of adult macaque monkeys after global cerebral ischemia. J Neurosci Res 81, 776-788

22. Suzuki, S., Yamashita, T., Tanaka, K., Hattori, H., Sawamoto, K., Okano, H., and Suzuki, N. (2005) Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats. J Cereb Blood Flow Metab 25, 685-693

23. Kanuka, H., Hiratou, T., Igaki, T., Kanda, H., Kuranaga, E., Sawamoto, K., Aigaki, T., Okano, H., and Miura, M. (2005) Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity. Biochim Biophys Acta 1726, 225-237

24. Hirota, Y., Sawamoto, K., Takahashi, K., Ueda, R., and Okano, H. (2005) The transmembrane protein, Tincar, is involved in the development of the compound eye in Drosophila melanogaster. Dev Genes Evol 215, 90-96

25. Yoshizaki, T., Inaji, M., Kouike, H., Shimazaki, T., Sawamoto, K., Ando, K., Date, I., Kobayashi, K., Suhara, T., Uchiyama, Y., and Okano, H. (2004) Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells. Neurosci Lett 363, 33-37

26. Yamashima, T., Tonchev, A.B., Vachkov, I.H., Popivanova, B.K., Seki, T., Sawamoto, K., and Okano, H. (2004) Vascular adventitia generates neuronal progenitors in the monkey hippocampus after ischemia. Hippocampus 14, 861-875

27. Unezaki, S., Nishizawa, M., Okuda-Ashitaka, E., Masu, Y., Mukai, M., Kobayashi, S., Sawamoto, K., Okano, H., and Ito, S. (2004) Characterization of the isoforms of MOVO zinc finger protein, a mouse homologue of Drosophila Ovo, as transcription factors. Gene 336, 47-58

28. Tokunaga, A., Kohyama, J., Yoshida, T., Nakao, K., Sawamoto, K., and Okano, H. (2004) Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain. J Neurochem 90, 142-154

29. Uchida, M., Hanai, S., Uematsu, N., Sawamoto, K., Okano, H., Miwa, M., and Uchida, K. (2002) Overexpression of poly(ADP-ribose) polymerase disrupts organization of cytoskeletal F-actin and tissue polarity in Drosophila. J Biol Chem 277, 6696-6702

30. Ogawa, Y., Sawamoto, K., Miyata, T., Miyao, S., Watanabe, M., Nakamura, M., Bregman, B.S., Koike, M., Uchiyama, Y., Toyama, Y., and Okano, H. (2002) Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. J Neurosci Res 69, 925-933

31. Kuranaga, E., Kanuka, H., Igaki, T., Sawamoto, K., Ichijo, H., Okano, H., and Miura, M. (2002) Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila. Nat Cell Biol 4, 705-710

32. Hirota, Y., Sawamoto, K., and Okano, H. (2002) tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila. Mech Dev 119 Suppl 1, S279-283

33. Uchida, M., Hanai, S., Uematsu, N., Sawamoto, K., Okano, H., Miwa, M., and Uchida, K. (2001) Genetic and functional analysis of PARP, a DNA strand break-binding enzyme. Mutat Res 477, 89-96

34. Sawamoto, K., Yamamoto, A., Kawaguchi, A., Yamaguchi, M., Mori, K., Goldman, S.A., and Okano, H. (2001) Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent proteins regulated by stage-specific neural promoters. J Neurosci Res 65, 220-227

35. Sawamoto, K., Nakao, N., Kobayashi, K., Matsushita, N., Takahashi, H., Kakishita, K., Yamamoto, A., Yoshizaki, T., Terashima, T., Murakami, F., Itakura, T., and Okano, H. (2001) Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proc Natl Acad Sci U S A 98, 6423-6428

36. Sawamoto, K., Nakao, N., Kakishita, K., Ogawa, Y., Toyama, Y., Yamamoto, A., Yamaguchi, M., Mori, K., Goldman, S.A., Itakura, T., and Okano, H. (2001) Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. J Neurosci 21, 3895-3903

37. Kawaguchi, A., Miyata, T., Sawamoto, K., Takashita, N., Murayama, A., Akamatsu, W., Ogawa, M., Okabe, M., Tano, Y., Goldman, S.A., and Okano, H. (2001) Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells. Mol Cell Neurosci 17, 259-273

38. Taguchi, A., Sawamoto, K., and Okano, H. (2000) Mutations modulating the Argos-regulated signaling pathway in Drosophila eye development. Genetics 154, 1639-1648

39. Tabuchi, K., Sawamoto, K., Suzuki, E., Ozaki, K., Sone, M., Hama, C., Tanifuji-Morimoto, T., Yuasa, Y., Yoshihara, Y., Nose, A., and Okano, H. (2000) GAL4/UAS-WGA system as a powerful tool for tracing Drosophila transsynaptic neural pathways. J Neurosci Res 59, 94-99

40. Kaneko, Y., Sakakibara, S., Imai, T., Suzuki, A., Nakamura, Y., Sawamoto, K., Ogawa, Y., Toyama, Y., Miyata, T., and Okano, H. (2000) Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells. Dev Neurosci 22, 139-153

41. Jin, M.H., Sawamoto, K., Ito, M., and Okano, H. (2000) The interaction between the Drosophila secreted protein argos and the epidermal growth factor receptor inhibits dimerization of the receptor and binding of secreted spitz to the receptor. Mol Cell Biol 20, 2098-2107

42. Igaki, T., Kanuka, H., Inohara, N., Sawamoto, K., Nunez, G., Okano, H., and Miura, M. (2000) Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death. Proc Natl Acad Sci U S A 97, 662-667

43. Yoshihara, Y., Mizuno, T., Nakahira, M., Kawasaki, M., Watanabe, Y., Kagamiyama, H., Jishage, K., Ueda, O., Suzuki, H., Tabuchi, K., Sawamoto, K., Okano, H., Noda, T., and Mori, K. (1999) A genetic approach to visualization of multisynaptic neural pathways using plant lectin transgene. Neuron 22, 33-41

44. Sawamoto, K., Yamada, C., Kishida, S., Hirota, Y., Taguchi, A., Kikuchi, A., and Okano, H. (1999) Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development. Oncogene 18, 1967-1974

45. Sawamoto, K., Winge, P., Koyama, S., Hirota, Y., Yamada, C., Miyao, S., Yoshikawa, S., Jin, M.H., Kikuchi, A., and Okano, H. (1999) The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway. J Cell Biol 146, 361-372

46. Kanuka, H., Sawamoto, K., Inohara, N., Matsuno, K., Okano, H., and Miura, M. (1999) Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator. Mol Cell 4, 757-769

47. Kanuka, H., Hisahara, S., Sawamoto, K., Shoji, S., Okano, H., and Miura, M. (1999) Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: implicated mechanisms for caspase activation. Proc Natl Acad Sci U S A 96, 145-150

48. Hirota, Y., Okabe, M., Imai, T., Kurusu, M., Yamamoto, A., Miyao, S., Nakamura, M., Sawamoto, K., and Okano, H. (1999) Musashi and seven in absentia downregulate Tramtrack through distinct mechanisms in Drosophila eye development. Mech Dev 87, 93-101

49. Fujimoto, J., Sawamoto, K., Okabe, M., Takagi, Y., Tezuka, T., Yoshikawa, S., Ryo, H., Okano, H., and Yamamoto, T. (1999) Cloning and characterization of Dfak56, a homolog of focal adhesion kinase, in Drosophila melanogaster. J Biol Chem 274, 29196-29201

50. Tabuchi, K., Yoshikawa, S., Yuasa, Y., Sawamoto, K., and Okano, H. (1998) A novel Drosophila paired-like homeobox gene related to Caenorhabditis elegans unc-4 is expressed in subsets of postmitotic neurons and epidermal cells. Neurosci Lett 257, 49-52

51. Sawamoto, K., Taguchi, A., Hirota, Y., Yamada, C., Jin, M.H., and Okano, H. (1998) Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway. Cell Death Differ 5, 262-270

52. Saito, T., Sawamoto, K., Okano, H., Anderson, D.J., and Mikoshiba, K. (1998) Mammalian BarH homologue is a potential regulator of neural bHLH genes. Dev Biol 199, 216-225

53. Sawamoto, K., and Takahashi, N. (1997) Modulation of hepatocyte function by changing the cell shape in primary culture. In Vitro Cell Dev Biol Anim 33, 569-574

54. Sawamoto, K., Okabe, M., Tanimura, T., Mikoshiba, K., Nishida, Y., and Okano, H. (1996) The Drosophila secreted protein Argos regulates signal transduction in the Ras/MAPK pathway. Dev Biol 178, 13-22

55. Sawamoto, K., Okabe, M., Tanimura, T., Hayashi, S., Mikoshiba, K., and Okano, H. (1996) argos Is required for projection of photoreceptor axons during optic lobe development in Drosophila. Dev Dyn 205, 162-171

56. Okabe, M., Sawamoto, K., and Okano, H. (1996) The function of the Drosophila argos gene product in the development of embryonic chordotonal organs. Dev Biol 175, 37-49

57. Sawamoto, K., and Takahashi, N. (1995) Changes in the organelle arrangement in primary cultured hepatocytes following the formation of cytoskeleton. Int J Tissue React 17, 205-210

58. Sawamoto, K., Okano, H., Kobayakawa, Y., Hayashi, S., Mikoshiba, K., and Tanimura, T. (1994) The function of argos in regulating cell fate decisions during Drosophila eye and wing vein development. Dev Biol 164, 267-276

59. Okano, H., Yoshikawa, S., Suzuki, A., Ueno, N., Kaizu, M., Okabe, M., Takahashi, T., Matsumoto, M., Sawamoto, K., and Mikoshiba, K. (1994) Cloning of a Drosophila melanogaster homologue of the mouse type-I bone morphogenetic proteins-2/-4 receptor: a potential decapentaplegic receptor. Gene 148, 203-209

60. Okano, H., Hayashi, S., Tanimura, T., Sawamoto, K., Yoshikawa, S., Watanabe, J., Iwasaki, M., Hirose, S., Mikoshiba, K., and Montell, C. (1992) Regulation of Drosophila neural development by a putative secreted protein. Differentiation 52, 1-11