Original papers 英文原著論文

2024

Ogino T, Agetsuma M, Sawada M, Inada H, Nabekura J and Sawamoto K.
Astrocytic activation increases blood flow in the adult olfactory bulb.
Mol Brain 17:52 (2024)
DOI:10.1186/s13041-024-01126-1
https://doi.org/10.1186/s13041-024-01126-1
https://pubmed.ncbi.nlm.nih.gov/39107815/

Ogino T, Saito A, Sawada M, Takemura S, Nagase J, Kawase H, Inada H, Herranz-Pérez V, Mukouyama Y, Ema M, García-Verdugo JM, Nabekura J and Sawamoto K.
Neuronal migration depends on blood flow in the adult brain.
eLife 99502.1 (2024)
DOI:10.7554/eLife.99502.1
https://doi.org/10.7554/eLife.99502.1

Matsumoto M, Matsushita K, Hane M, Wen C, Kurematsu C, Ota H, Nguyen HB, Thai TQ, Herranz-Pérez V, Sawada M, Fujimoto K, García-Verdugo JM, Kimura KD, Seki T, Sato C, Ohno N, Sawamoto K. Neuraminidase inhibition promotes the collective migration of neurons and recovery of brain function. EMBO Mol. Med. Online ahead of print. (2024)
DOI:10.1038/s44321-024-00073-7
https://doi.org/10.1038/s44321-024-00073-7
https://pubmed.ncbi.nlm.nih.gov/38789599/

Nakajima C, Sawada M, Umeda E, Takagi Y, Nakashima N, Kuboyama K, Kaneko N, Yamamoto S, Nakamura H, Shimada N, Nakamura K, Matsuno K, Uesugi S, Vepřek NA, Küllmer F, Nasufović V, Uchiyama H, Nakada M, Otsuka Y, Ito Y, Herranz-Pérez V, García-Verdugo JM, Ohno N, Arndt HD, Trauner D, Tabata Y, Igarashi M, Sawamoto K.
Identification of the growth cone as a probe and driver of neuronal migration in the injured brain.
Nat. Commun. 15, 1877 (2024)
DOI:10.1038/s41467-024-45825-8
https://doi.org/10.1038/s41467-024-45825-8
https://pubmed.ncbi.nlm.nih.gov/38461182/

2023

Sawada M, Hamaguchi A, Mano N, Yoshida Y, Uemura A, Sawamoto K.
PlexinD1 signaling controls domain-specific dendritic development in newborn neurons in the postnatal olfactory bulb. 
Frontiers in Neuroscience 17, 1143130 (2023)
DOI:10.3389/fnins.2023.1143130
https://doi.org/10.3389/fnins.2023.1143130
https://pubmed.ncbi.nlm.nih.gov/37534039/

Wen C, Matsumoto M, Sawada M, Sawamoto K, Kimura KD.
Seg2Link: an efficient and versatile solution for semi-automatic cell segmentation in 3D image stacks.
Sci Rep 13:7109 (2023)
DOI:10.1038/s41598-023-34232-6
https://doi.org/10.1038/s41598-023-34232-6
https://pubmed.ncbi.nlm.nih.gov/37217545/

Ieda N, Sawada M, Oguchi R, Itoh M, Hirakata S, Saitoh D, Nakao A, Kawaguchi M, Sawamoto K, Yoshihara T, Mori Y, Nakagawa H.
An Optochemical Oxygen Scavenger Enabling Spatiotemporal Control of Hypoxia.
Angew Chem Int Ed Engl 16;e202217585 (2023)
DOI:10.1002/anie.202217585
https://doi.org/10.1002/anie.202217585
https://pubmed.ncbi.nlm.nih.gov/36929683/

Ohno Y, Nakajima C, Ajioka I, Muraoka T, Yaguchi A, Fujioka T, Akimoto S, Matsuo M, Lotfy A, Nakamura S, Herranz-Pérez V, García-Verdugo JM, Matsukawa N, Kaneko N, Sawamoto K.
Amphiphilic peptide-tagged N-cadherin forms radial glial-like fibers that enhance neuronal migration in injured brain and promote sensorimotor recovery.
Biomaterials 294:122003 (2023)
DOI:10.1016/j.biomaterials.2023.122003
https://doi.org/10.1016/j.biomaterials.2023.122003
https://pubmed.ncbi.nlm.nih.gov/36736095/

2022

Tsuboi Y, Ito A, Otsuka T, Murakami H, Sawada M, Sawamoto K.
Habilitation Improves Mouse Gait Development Following Neonatal Brain Injury.
Prog Rehabil Med 7:20220061 (2022)
DOI:10.2490/prm.20220061
https://doi.org/10.2490/prm.20220061
https://pubmed.ncbi.nlm.nih.gov/36479304/

Namiki J, Suzuki S, Shibata S, Kubota Y, Kaneko N, Yoshida K, Yamaguchi R, Matsuzaki Y, Masuda T, Ishihama Y, Sawamoto K, Okano H.
Chitinase-like protein 3: A novel niche factor for mouse neural stem cells.
Stem Cell Reports 17(12):2704-2717 (2022)
DOI:10.1016/j.stemcr.2022.10.012
https://doi.org/10.1016/j.stemcr.2022.10.012
https://pubmed.ncbi.nlm.nih.gov/36368330/

Kurematsu C, Sawada M, Ohmuraya M, Tanaka M, Kuboyama K, Ogino T, Matsumoto M, Oishi H, Inada H, Ishido Y, Sakakibara Y, Nguyen HB, Thai TQ, Kohsaka S, Ohno N, Yamada MK, Asai M, Sokabe M, Nabekura J, Asano K, Tanaka M, Sawamoto K.
Synaptic pruning of murine adult-born neurons by microglia depends on phosphatidylserine.
J. Exp. Med. 219 (4): e20202304 (2022)
DOI:10.1084/jem.20202304
https://doi.org/10.1084/jem.20202304
https://pubmed.ncbi.nlm.nih.gov/35297954/

2021

Yaguchi A, Oshikawa M, Watanabe G, Hara C, Kaneko N, Sawamoto K, Hiramatsu H, Uchida N, Muraoka T and Ajioka I.
Efficient Protein Incorporation and Release by a Jigsaw-Shaped Self-Assembling Peptide Hydrogel for Injured Brain Regeneration.
Nat Commun 12: 6623 (2021)
DOI:10.1038/s41467-021-26896-3
https://doi.org/10.1038/s41467-021-26896-3
https://pubmed.ncbi.nlm.nih.gov/34799548/

Ota Y, Kubota Y, Hotta Y, Matsumoto M, Matsuyama N, Kato T, Hamakawa T, Kataoka T, Kimura K, Sawamoto K and Yasui T.
Change in the Central Control of the Bladder Function of Rats with Focal Cerebral Infarction Induced by Photochemically-Induced Thrombosis.
PLOS ONE 16(11):e0255200. (2021)
DOI:10.1371/journal.pone.0255200
https://doi.org/10.1371/journal.pone.0255200
https://pubmed.ncbi.nlm.nih.gov/34752461/

Okada M, Kawagoe Y, Sato Y, Nozumi M, Ishikawa Y, Tamada A, Yamazaki H, Sekino Y, Kanemura Y, Shinmyo Y, Kawasaki H, Kaneko N, Sawamoto K, Fujii Y and Igarashi K.
Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates.
Mol Brain 14: 66 (2021)
DOI:10.1186/s13041-021-00755-0
https://doi.org/10.1186/s13041-021-00755-0
https://pubmed.ncbi.nlm.nih.gov/33832520/

Ito N, Riyadh MA, Ahmad SAI, Hattori S, Kanemura Y, Kiyonari H, Abe T, Furuta Y, Shinmyo Y, Kaneko N, Hirota Y, Lupo G, Hatakeyama J, Abdulhaleem MFA, Anam MB, Yamaguchi M, Takeo T, Takebayashi H, Takebayashi M, Oike Y, Nakagata N, Shimamura K, Holtzman MJ, Takahashi Y, Guillemot F, Miyakawa T, Sawamoto K, and Ohta K.
Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone.
Sci Transl Med 13: eaay7896 (2021)
DOI:10.1126/scitranslmed.aay7896
https://doi.org/10.1126/scitranslmed.aay7896
https://pubmed.ncbi.nlm.nih.gov/33790026/

Koyanagi I, Sonomura K, Naoi T, Ohnishi T, Kaneko N, Sawamoto K, Sato TA, Sakaguchi M.
Metabolic fingerprints of fear memory consolidation during sleep.
Mol Brain 14: 30(2021)
DOI:10.1186/s13041-021-00733-6
https://doi.org/10.1186/s13041-021-00733-6
https://pubmed.ncbi.nlm.nih.gov/33568175/

2020

Sawada M, Matsumoto M, Narita K, Kumamoto N, Ugawa S, Takeda S, Sawamoto K.
In vitro time-lapse imaging of primary cilium in migrating neuroblasts.
Bio-protocol 10(22): e3823 (2020) 
DOI:10.21769/BioProtoc.3823
https://doi.org/10.21769/BioProtoc.3823
https://pubmed.ncbi.nlm.nih.gov/33659475/

Kaneko N, Nakamura S, Sawamoto K.
Effects of interferon-alpha on hippocampal neurogenesis and behavior in common marmosets.
Mol Brain 13: 98 (2020)
DOI:10.1186/s13041-020-00639-9
https://doi.org/10.1186/s13041-020-00639-9
https://pubmed.ncbi.nlm.nih.gov/32590991/

Kumar D, Koyanagi I, Carrier-Ruiz A, Vergara P, Srinivasan S, Sugaya Y, Kasuya M, Yu T, Vogt KE, Muratani M, Ohnishi T, Singh S, Teixeira CM, Chérasse Y, Naoi T, Wang S, Nondhalee P, Osman BAH, Kaneko N, Sawamoto K, Kernie SG, Sakurai T, McHugh TJ, Kano M, Yanagisawa M, Sakaguchi M.
Sparseactivity of hippocampal adult-born neurons during REM sleep is necessary for memory consolidation.
Neuron 2020 May 20:S0896-6273(20)30354-8(2020)
DOI:10.1016/j.neuron.2020.05.008
https://doi.org/10.1016/j.neuron.2020.05.008
https://www.cell.com/neuron/fulltext/S0896-6273(20)30354-8
https://pubmed.ncbi.nlm.nih.gov/32502462/

Akter M, Kaneko N, Herranz-Perez V, Nakamura S, Oishi H, Garcia-Verdugo JM, Sawamoto K.
Dynamic changes in the neurogenic potential in the ventricular-subventricular zone of common marmoset during postnatal brain development.
Cerebral Cortex 30: 4092-4109 (2020)
DOI:10.1093/cercor/bhaa031
https://doi.org/10.1093/cercor/bhaa031
https://pubmed.ncbi.nlm.nih.gov/32108222/

2019

Matsumoto M, Sawada M, García-González D, Herranz-Pérez V, OginoT, Nguyen HB, Thai TQ, Narita K, Kumamoto N, Ugawa S, Saito Y, Takeda S, Kaneko N, Khodosevich K, Monyer H, García-Verdugo JM, Ohno N, Sawamoto K.
Dynamic changes in ultrastructure of the primary cilium in migrating neuroblasts in the postnatal brain.
J Neurosci 39: 9967-9988 (2019)
DOI:10.1523/JNEUROSCI.1503-19.2019
https://doi.org/10.1523/JNEUROSCI.1503-19.2019
https://pubmed.ncbi.nlm.nih.gov/31685650/

Guo T, Tanaka T, Matsumoto M, Kaneko K, Unzai T, Ogino Y, Aotani D, Kusakabe T, Iwakura H, Miyazawa T, Sawamoto K, Minokoshi Y, Masuzaki H, Inagaki N, Nakao K.
A combination of dietary fat intake and nicotine exposure enhances CB1 endocannabinoid receptor expression in hypothalamic nuclei in male mice.
Neurosci Lett 714: January 1, 134550(2019) 
DOI:10.1016/j.neulet.2019.134550
https://doi.org/10.1016/j.neulet.2019.134550
https://pubmed.ncbi.nlm.nih.gov/31634502/

2018

Sato Y, Kiyozumi D, Futaki S, Nakano I, Shimono C, Kaneko N, Ikawa M, Okabe M, Sawamoto K, Sekiguchi K.
Ventricular-subventricular zone fractones are speckled basement membranes that function as a neural stem cell niche.
Mol Biol Cell 30: 56-68 (2018)
DOI:10.1091/mbc.e18-05-0286
https://doi.org/10.1091/mbc.e18-05-0286
https://pubmed.ncbi.nlm.nih.gov/30379609/

Kaneko N, Herranz-Pérez V, Otsuka T, Sano H, Ohno N, Omata T, Nguyen HB, Thai TQ, Nambu A, Kawaguchi Y, García-Verdugo JM, Sawamoto K.
New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration.
Sci Adv 4: eaav0618 (2018)
DOI: 10.1126/sciadv.aav0618
https://doi.org/10.1126/sciadv.aav0618
http://advances.sciencemag.org/content/4/12/eaav0618

Minegishi T, Uesugi Y, Kaneko N, Yoshida W, Sawamoto K, Inagaki N.
Shootin1b mediates a mechanical clutch to produce force for neuronal migration.
Cell Rep 25: 624-639.e6(2018)
DOI: 10.1016/j.celrep.2018.09.068
 https://doi.org/10.1016/j.celrep.2018.09.068
https://pubmed.ncbi.nlm.nih.gov/30332643/

Aoyagi Y, Hibi T, Kimori Y, Sawada M, Kawakami R, Sawamoto K, Nemoto T.
Heterogeneous distribution of doublecortin-expressing cells surrounding the rostral migratory stream in the juvenile mouse.
J Comp Neurol 526(16), 2631-2646 (2018)
DOI:10.1002/cne.24521
https://doi.org/10.1002/cne.24521
https://pubmed.ncbi.nlm.nih.gov/30136724/

Fujikake K, Sawada M, Hikita T, Seto Y, Kaneko N, Herranz-Pérez V, Dohi N, Homma N, Osaga S, Yanagawa Y, Akaike T, García-Verdugo JM, Hattori M, Sobue K, Sawamoto K.
Detachment of chain-forming new neurons by Fyn-mediated control of cell-cell adhesion in the postnatal brain.
J Neurosci 38: 4598-4609 (2018)
DOI:10.1523/JNEUROSCI.1960-17.2018
https://doi.org/10.1523/JNEUROSCI.1960-17.2018
https://pubmed.ncbi.nlm.nih.gov/29661967/

Sawada M, Ohno N, Kawaguchi M, Huang S, Hikita T, Sakurai Y, Nguyen HB, Thai TQ, Ishido Y, Yoshida Y, Nakagawa H, Uemura A, Sawamoto K.
PlexinD1 signaling controls morphological changes and migration termination in newborn neurons.
EMBO J 37: e97404 (2018)
DOI:10.15252/embj.201797404    
http://emboj.embopress.org/cgi/doi/10.15252/embj.201797404
https://pubmed.ncbi.nlm.nih.gov/29348324/

Jinnou H, Sawada M, Kawase K, Kaneko N, Herranz-Pérez V, Miyamoto T, Kawaue T, Miyata T, Tabata Y, Akaike T, García-Verdugo JM, Ajioka I, Saitoh S, Sawamoto K.
Radial glial fibers promote neuronal migration and functional recovery after neonatal brain injury.
Cell Stem Cell 22: 128-137 (2018)
DOI:10.1016/j.stem.2017.11.005
https://doi.org/10.1016/j.stem.2017.11.005
https://pubmed.ncbi.nlm.nih.gov/29276142/

2017

Takagishi M, Sawada M, Ohata S, Asai N, Enomoto A, Takahashi K, Weng L, Ushida K, Ara H, Matsui S, Kaibuchi K, Sawamoto K, Takahashi M.
Daple coordinates planar polarized microtubule dynamics in ependymal cells and contributes to hydrocephalus.
Cell Rep 20(4), 960–972 (2017)
DOI:10.1016/j.celrep.2017.06.089
https://doi.org/10.1016/j.celrep.2017.06.089
https://pubmed.ncbi.nlm.nih.gov/28746879/

Cebrián-Silla A, Alfaro-Cervelló C, Herranz-Pérez V, Kaneko N, Park DH, Sawamoto K, Alvarez-Buylla A, Lim DA, García-Verdugo JM.
Unique organization of the nuclear envelope in the post-natal quiescent neural stem cells. 
Stem Cell Reports pii: S2213-6711(17)30231-X (2017)
DOI:10.1016/j.stemcr.2017.05.024.
https://doi.org/10.1016/j.stemcr.2017.05.024.
https://pubmed.ncbi.nlm.nih.gov/28648897/

Oshikawa M, Okada K, Kaneko N, Sawamoto K, Ajioka I.
Affinity-Immobilization of VEGF on Laminin Porous Sponge Enhances Angiogenesis in the Ischemic Brain.
Adv Healthcare Mater 2017: 1700183(2017)
DOI:10.1002/adhm.201700183
https://doi.org/10.1002/adhm.201700183
https://pubmed.ncbi.nlm.nih.gov/28488337/

Fujioka T, Kaneko N, Ajioka I, Nakaguchi K, Omata T, Ohba H, Fässler R, García-Verdugo JM, Sekiguchi K, Matsukawa N, Sawamoto K.
β1 integrin signaling promotes neuronal migration along vascular scaffolds in the post-stroke brain.
EBioMedicine 16:195-203 (2017) 
DOI: 10.1016/j.ebiom.2017.01.005
https://doi.org/10.1016/j.ebiom.2017.01.005
https://pubmed.ncbi.nlm.nih.gov/28153772/

2016

Matsunami K, Nishida N, Kaneko N, Ikeo K, Toyo-Oka L, Takeuchi H, Matsuura K, Tamori A, Nomura H, Yoshiji H, Imamura M, Masaki N, Hayakawa T, Ide T, Shimada N, Ikeda F, Hino K, Nishiguchi S, Okuse C, Nojiri S, Sawamoto K, Tokunaga K, Joh T, Tanaka Y.
Genome-Wide Association Study Identifies ZNF354C Variants Associated with Depression from Interferon-Based Therapy for Chronic Hepatitis C. 
PLoS One 11(10):e0164418 (2016)
DOI:10.1371/journal.pone.0164418
https://doi.org/10.1371/journal.pone.0164418
https://pubmed.ncbi.nlm.nih.gov/27723809/

Miyake M, Ito Y, Sawada M, Sakai K, Suzuki H, Sakamoto T, Sawamoto K, Kamijima M.
Subchronic inhalation exposure to 2-ethyl-1-hexanol impairs the mouse olfactory bulb via injury and subsequent repair of the nasal olfactory epithelium. 
Arch Toxicol 90: 1949-1958 (2016)
DOI:10.1007/s00204-016-1699-6
https://doi.org/10.1007/s00204-016-1699-6
http://www.ncbi.nlm.nih.gov/pubmed/27055686

Ogino T, Sawada M, Takase H, Nakai C, Herranz-Pérez V, Cebrián-Silla A, Kaneko N, Manuel García-Verdugo J, Sawamoto K.
Characterization of multiciliated ependymal cells that emerge in the neurogenic niche of the aged zebrafish brain.
J Comp Neurol 524: 2982-2992(2016)
DOI:10.1002/cne.24001
https://doi.org/10.1002/cne.24001
http://www.ncbi.nlm.nih.gov/pubmed/26991819

Hirota Y, Sawada M, Huang SH, Ogino T, Ohata S, Kubo A and Sawamoto K.
Roles of Wnt signaling in the neurogenic niche of the adult mouse ventricular-subventricular zone.
Neurochem Res 41:222-230 (2016)  
DOI:10.1007/s11064-015-1766-z
https://doi.org/10.1007/s11064-015-1766-z
http://www.ncbi.nlm.nih.gov/pubmed/26572545

2015

Yamagishi S, Yamada K, Sawada M, Nakano S, Mori N, Sawamoto K and Sato K.
Netrin-5 is highly expressed in neurogenic regions of the adult brain. 
Front Cell Neurosci 9:146 (2015)
DOI:10.3389/fncel.2015.00146
https://doi.org/10.3389/fncel.2015.00146
https://pubmed.ncbi.nlm.nih.gov/25941474/

Zheng LS, Kaneko N and Sawamoto K.
Minocycline treatment ameliorates interferon-alpha-induced neurogenic defects and depression-like behaviors in mice.
Front Cell Neurosci 9:5(2015)
DOI:10.3389/fncel.2015.00005
https://doi.org/10.3389/fncel.2015.00005
https://pubmed.ncbi.nlm.nih.gov/25674053/

Ajioka I, Jinnou H, Okada K, Sawada M, Saitoh S, Sawamoto K.
Enhancement of neuroblast migration into the injured cerebral cortex using laminin-containing porous sponge.
Tissue Eng Part A 21: 193-201 (2015)
DOI:10.1089/ten.tea.2014.0080
https://doi.org/10.1089/ten.tea.2014.0080
https://pubmed.ncbi.nlm.nih.gov/25010638/

2014

Ota H, Hikita T, Sawada M, Nishioka T, Matsumoto M, Komura M, Ohno A, Kamiya Y, Miyamoto T, Asai N, Enomoto A, Takahashi M, Kaibuchi K, Sobue K, Sawamoto K.
Speed control for neuronal migration in the postnatal brain by Gmip-mediated local inactivation of RhoA.
Nat Commun 5: 4532 (2014)
DOI:10.1038/ncomms5532
https://doi.org/10.1038/ncomms5532
https://pubmed.ncbi.nlm.nih.gov/25074242/

Zheng LS, Hitoshi S, Kaneko N, Takao K, Miyakawa T, Tanaka Y, Xia H, Kalinke U, Kudo K, Kanba S, Ikenaka K, Sawamoto K.
Mechanisms for interferon-alpha-induced depression and neural stem cell dysfunction.
Stem Cell Rep 3: 73-84 (2014)
DOI:10.1016/j.stemcr.2014.05.015
https://doi.org/10.1016/j.stemcr.2014.05.015
http://www.ncbi.nlm.nih.gov/pubmed/25068123

Hikita T, Ohno A, Sawada M, Ota H, Sawamoto K.
Rac1-mediated indentation of resting neurons promotes the chain migration of new neurons in the rostral migratory stream of postnatal mouse brain.
J Neurochem 128: 790-797 (2014)
DOI:10.1111/jnc.12518
https://doi.org/10.1111/jnc.12518
https://pubmed.ncbi.nlm.nih.gov/24188721/

2013

Ota H, Hikita T, Nishioka T, Matsumoto M, Ito J, Asai N, Enomoto A, Takahashi M, Kaibuchi K, Sobue K, Sawamoto K.
Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain.
Biochem Biophys Res Commun 442: 16-21(2013)
DOI:10.1016/j.bbrc.2013.10.126
https://doi.org/10.1016/j.bbrc.2013.10.126
https://pubmed.ncbi.nlm.nih.gov/24211587/

Kishimoto N, Asakawa K, Madelaine R, Blader P, Kawakami K, Sawamoto K.
Interhemispheric asymmetry of olfactory input-dependent neuronal specification in the adult brain.
Nat Neurosci 16: 884-888(2013)
DOI: 10.1038/nn.3409
https://doi.org/10.1038/nn.3409
http://www.ncbi.nlm.nih.gov/pubmed/23685722

Yamagata M, Yamamoto A, Kako E, Kaneko N, Matsubara K, Sakai K, Sawamoto K, Ueda M.
Human dental pulp-derived stem cells protect against hypoxic-ischemic brain injury in neonatal mice.
Stroke 44: 551-554 (2013)
DOI:10.1161/STROKEAHA.112.676759
https://doi.org/10.1161/strokeaha.112.676759
http://www.ncbi.nlm.nih.gov/pubmed/23238858

2012

Kato Y, Kaneko N, Sawada M, Ito K, Arakawa S, Murakami S, Sawamoto K.
A subtype-specific critical period for neurogenesis in the postnatal development of mouse olfactory glomeruli.
PLoS ONE 7 (11): e48431(2012)
DOI:10.1371/journal.pone.0048431
https://doi.org/10.1371/journal.pone.0048431
https://pubmed.ncbi.nlm.nih.gov/23133633/

Nakaguchi K, Jinnou H, Kaneko N, Sawada M, Hikita T, Saitoh S, Tabata Y, Sawamoto K.
Growth factors released from gelatin hydrogel microspheres increase new neurons in the adult mouse brain.
Stem Cells Int 2012, Article ID 915160, 7 pages, (2012)
DOI:10.1155/2012/915160
https://doi.org/10.1155/2012/915160
https://pubmed.ncbi.nlm.nih.gov/23093979/

Kako E, Kaneko N, Aoyama M, Hida H, Takebayashi H, Ikenaka K, Asai K, Togari H, Sobue K, Sawamoto K.
Subventricular-zone derived oligodendrogenesis in injured neonatal white-matter in mice enhanced by a nonerythropoietic EPO derivative.
Stem Cells 30: 2234-2247 (2012)
DOI: 10.1002/stem.1202
https://doi.org/10.1002/stem.1202
https://pubmed.ncbi.nlm.nih.gov/22890889/

Hirota Y, Sawada M, Kida YS, Huang S, Yamada O, Sakaguchi M, Ogura T, Okano H, Sawamoto K.
Roles of planar cell polarity signaling in maturation of neuronal precursor cells in the postnatal mouse olfactory bulb.
Stem Cells 30: 1726-1733 (2012)
DOI: 10.1002/stem.1137
https://doi.org/10.1002/stem.1137
http://www.ncbi.nlm.nih.gov/pubmed/22628050

Suyama S, Sunabori T, Kanki H, Sawamoto K, Gachet C, Koizumi S, Okano H.
Purinergic signaling promotes proliferation of adult mouse subventricular zone cells.
J Neurosci 32: 9238-9247(2012)
DOI:10.1523/JNEUROSCI.4001-11.2012
https://doi.org/10.1523/jneurosci.4001-11.2012
https://pubmed.ncbi.nlm.nih.gov/22764232/

Kishimoto N, Shimizu K, Sawamoto K.
Neuronal regeneration in a zebrafish model of adult brain injury.
Dis Models Mech 5: 200-209 (2012)
DOI:10.1242/dmm.007336
https://doi.org/10.1242/dmm.007336
https://pubmed.ncbi.nlm.nih.gov/22028327/

Shinohara R, Thumkeo D, Kamijo H, Kaneko N, Sawamoto K, Watanabe K, Takebayashi H, Kiyonari H, Ishizaki T, Furuyashiki T, Narumia S.
A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors.
Nat Neurosci 15: 373-380(2012)
DOI:10.1038/nn.3020
https://doi.org/10.1038/nn.3020
https://pubmed.ncbi.nlm.nih.gov/22246438/

2011

Sawada M, Kaneko N, Inada H, Wake H, Kato Y, Yanagawa Y, Kobayashi K, Nemoto T, Nabekura J, Sawamoto K.
Sensory input regulates spatial and subtype-specific patterns of neuronal turnover in the adult olfactory bulb.
J Neurosci31:11587-11596 (2011)
DOI: 10.1523/JNEUROSCI.0614-11.2011
https://doi.org/10.1523/jneurosci.0614-11.2011
https://pubmed.ncbi.nlm.nih.gov/21832189/

Kishimoto N, Alfaro-Cervello C, Shimizu K, Asakawa K, Urasaki A, Nonaka S, Kawakami K, Garcia-Verdugo JM, Sawamoto K.
Migration of neuronal precursors from the telencephalic ventricular zone into the olfactory bulb in adult zebrafish.
J Comp Neurol 519:3549-3565(2011)
DOI: 10.1002/cne.22722
https://doi.org/10.1002/cne.22722
https://pubmed.ncbi.nlm.nih.gov/21800305/

Wang Y, Kaneko N, Asai N, Enomoto A, Isotani-Sakakibara M, Kato T, Asai M, Murakumo Y, Ota H, Hikita T, Namba T, Kuroda K, Kaibuchi K, Ming GL, Song H, Sawamoto K, Takahashi M.
Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain.
J Neurosci 31:8109-8122(2011)
DOI: 10.1523/JNEUROSCI.1130-11.2011
 https://doi.org/10.1523/jneurosci.1130-11.2011
https://pubmed.ncbi.nlm.nih.gov/21632933/

Sawamoto K, Hirota Y, Alfaro-Cervello C, Soriano-Navarro M, He X, Hayakawa-Yano Y, Yamada M, Hikishima K, Tabata H, Iwanami A, Nakajima K, Toyama Y, Itoh T, Alvarez-Buylla A, Garcia-Verdugo JM, Okano H.
Cellular composition and organization of the subventricular zone and rostral migratory stream in the adult and neonatal common marmoset brain.
J Comp Neurol 519:690-713 (2011)
DOI:10.1002/cne.22543
https://doi.org/10.1002/cne.22543
https://pubmed.ncbi.nlm.nih.gov/21246550/

Kato S, Aoyama M, Kakita H, Hida H, Kato I, Ito T, Goto T, Hussein MH, Sawamoto K, Togari H, Asai K.
Endogenous erythropoietin from astrocyte protects the oligodendrocyte precursor cell against hypoxic and reoxygenation injury.
J Neurosci Res 89:1566-1574 (2011)
DOI: 10.1002/jnr.22702
 https://doi.org/10.1002/jnr.22702
https://pubmed.ncbi.nlm.nih.gov/21833990/

Yamane J, Ishibashi S, Sakaguchi M, Kuroiwa T, Kanemura Y, Nakamura M, Miyoshi H, Sawamoto K, Toyama Y, Mizusawa H, Okano H.
Transplantation of human neural stem/progenitor cells overexpressing Galectin-1 improves functional recovery from focal brain ischemia in the Mongolian gerbil.
Mol Brain 4:35 (2011)
DOI: 10.1186/1756-6606-4-35
 https://doi.org/10.1186/1756-6606-4-35
https://pubmed.ncbi.nlm.nih.gov/21951913/

Imaizumi Y, Sakaguchi M, Morishita T, Ito M, Poirier F, Sawamoto K, Okano H.
Galectin-1 is expressed in early-type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus.
Mol Brain 4:7 (2011)
DOI: 10.1186/1756-6606-4-7
 https://doi.org/10.1186/1756-6606-4-7
https://pubmed.ncbi.nlm.nih.gov/21269521/

2010

Shimada M, Haruta M, Niida H, Sawamoto K, Nakanishi M.
Protein phosphatase 1gamma is responsible fordephosphorylation of histone H3 at Thr 11 after DNA damage.
EMBO Rep 11:883-889 (2010)
DOI:10.1038/embor.2010.152
https://doi.org/10.1038/embor.2010.152
https://pubmed.ncbi.nlm.nih.gov/20948546/

Sakaguchi M, Imaizumi Y, Shingo T, Tada H, Hayama K, Yamada O, Morishita T, Kadoya T, Uchiyama N, Shimazaki T, Kuno A, Poirier F, Hirabayashi J, Sawamoto K, Okano H.
Regulation of adult neural progenitor cells by Galectin-1/beta1 Integrin interaction.
J Neurochem 113:1516-1524 (2010)
DOI:10.1111/j.1471-4159.2010.06712.x
https://doi.org/10.1111/j.1471-4159.2010.06712.x
https://pubmed.ncbi.nlm.nih.gov/20367753/

Oki K, Kaneko N, Kanki H, Imai T, Suzuki N, Sawamoto K, Okano H.
Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia.
Neurosci Res 66:390-395 (2010)
DOI:10.1016/j.neures.2009.12.013
https://doi.org/10.1016/j.neures.2009.12.013
https://pubmed.ncbi.nlm.nih.gov/20036290/

Kojima T, Hirota Y, Ema M, Takahashi S, Miyoshi I, Okano H, Sawamoto K.
Subventricular zone-derived neural progenitor cells migrate along a blood vessel scaffold toward the post-stroke striatum.
Stem Cells 28:545-554 (2010)
DOI: 10.1002/stem.306
 https://doi.org/10.1002/stem.306
https://pubmed.ncbi.nlm.nih.gov/20073084/

Kaneko N, Marin O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K.
New Neurons Clear the Path of Astrocytic Processes for Their Rapid Migration in the Adult Brain.
Neuron 67:213-223(2010)
DOI:10.1016/j.neuron.2010.06.018
https://doi.org/10.1016/j.neuron.2010.06.018
https://pubmed.ncbi.nlm.nih.gov/20670830/
ライフサイエンス新着論文レビュー

Ikeda M, Hirota Y, Sakaguchi M, Yamada O, Kida YS, Ogura T, Otsuka T, Okano H, Sawamoto K.
Expression and Proliferation-Promoting Role of Diversin in the Neuronally Committed Precursor Cells Migrating in the Adult Mouse Brain.
Stem Cells 28:2017-2026 (2010)
DOI:10.1002/stem.516
https://doi.org/10.1002/stem.516
https://pubmed.ncbi.nlm.nih.gov/20827749/

Hirota Y, Meunier A, Huang S, Shimozawa T, Yamada O, Kida YS, Inoue M, Ito T, Kato H, Sakaguchi M, Sunabori T, Nakaya MA, Nonaka S, Ogura T, Higuchi H, Okano H, Spassky N, Sawamoto K.
Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II.
Development 137:3037-3046(2010)
DOI: 10.1242/dev.050120
 https://doi.org/10.1242/dev.050120
https://pubmed.ncbi.nlm.nih.gov/20685736/

Guirao B, Meunier A, Mortaud S, Aguilar A, Corsi JM, Strehl L, Hirota Y, Desoeuvre A, Boutin C, Han YG, Mirzadeh Z, Cremer H, Montcouquiol M, Sawamoto K, Spassky N.
Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia.
Nat Cell Biol 12:341-350(2010)
DOI:10.1038/ncb2040
https://doi.org/10.1038/ncb2040
https://pubmed.ncbi.nlm.nih.gov/20305650/

Mirzadeh Z, Doetsch F, Sawamoto K, Wichterle H, Alvarez-Buylla A.
The subventricular zone en-face: wholemount staining and ependymal flow.
J Vis Exp 39:1938(2010)
DOI:10.3791/1938
https://doi.org/10.3791/1938
https://pubmed.ncbi.nlm.nih.gov/20461052/

2009

Tamase A, Muraguchi T, Naka K, Tanaka S, Kinoshita M, Hoshii T, Ohmura M, Shugo H, Ooshio T, Nakada M, Sawamoto K, Onodera M, Matsumoto K, Oshima M, Asano M, Saya H, Okano H, Suda T, Hamada J, Hirao A.
Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin.
Proc Natl Acad Sci U S A 106:17163-17168(2009)
DOI:10.1073/pnas.0905016106
https://doi.org/10.1073/pnas.0905016106
https://pubmed.ncbi.nlm.nih.gov/19805150/

Suzuki T, Miyamoto H, Nakahari T, Inoue I, Suemoto T, Jiang B, Hirota Y, Itohara S, Saido TC, Tsumoto T, Sawamoto K, Hensch TK, Delgado-Escueta AV, Yamakawa K.
Efhc1 deficiency causes spontaneous myoclonus and increased seizure susceptibility.
Hum Mol Genet 18:1099-1109(2009)
DOI:10.1093/hmg/ddp006
https://doi.org/10.1093/hmg/ddp006
https://pubmed.ncbi.nlm.nih.gov/19147686/

Enomoto A, Asai N, Namba T, Wang Y, Kato T, Tanaka M, Tatsumi H, Taya S, Tsuboi D, Kuroda K, Kaneko N, Sawamoto K, Miyamoto R, Jijiwa M, Murakumo Y, Sokabe M, Seki T, Kaibuchi K, Takahashi M.
Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.
Neuron 63:774-787(2009)
DOI: 10.1016/j.neuron.2009.08.015
 https://doi.org/10.1016/j.neuron.2009.08.015
https://pubmed.ncbi.nlm.nih.gov/19778507/

2008

Sunabori T, Tokunaga A, Nagai T, Sawamoto K, Okabe M, Miyawaki A, Matsuzaki Y, Miyata T, Okano H.
Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors.
J Cell Sci 121:1204-1212 (2008)
DOI:10.1242/jcs.025064
https://doi.org/10.1242/jcs.025064
https://pubmed.ncbi.nlm.nih.gov/18349072/

Kohyama J, Kojima T, Takatsuka E, Yamashita T, Namiki J, Hsieh J, Gage FH, Namihira M, Okano H, Sawamoto K, Nakashima K.
Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain.
Proc Natl Acad Sci U S A 105:18012-18017(2008)
DOI:10.1073/pnas.0808417105
https://doi.org/10.1073/pnas.0808417105
https://pubmed.ncbi.nlm.nih.gov/19004774/

2007

Hirota Y, Ohshima T, Kaneko N, Ikeda M, Iwasato T, Kulkarni AB, Mikoshiba K, Okano H, Sawamoto K.
Cyclin-dependent kinase 5 is required for control of neuroblast migration in the postnatal subventricular zone.
J Neurosci 27:12829-12838 (2007)
DOI:10.1523/JNEUROSCI.1014-07.2007
https://doi.org/10.1523/jneurosci.1014-07.2007
https://pubmed.ncbi.nlm.nih.gov/18032654/

Adachi K, Mirzadeh Z, Sakaguchi M, Yamashita T, Nikolcheva T, Gotoh Y, Peltz G, Gong L, Kawase T, Alvarez-Buylla A, Okano H, Sawamoto K.
Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone.
Stem Cells 25:2827-2836 (2007)
DOI:10.1634/stemcells.2007-0177
https://doi.org/10.1634/stemcells.2007-0177
https://pubmed.ncbi.nlm.nih.gov/17673525/

2006

Sawamoto K, Wichterle H, Gonzalez-Perez O, Cholfin JA, Yamada M, Spassky N, Murcia NS, Garcia-Verdugo JM, Marin O, Rubenstein JL, Tessier-Lavigne M, Okano H, Alvarez-Buylla A.
New neurons follow the flow of cerebrospinal fluid in the adult brain.
Science 311:629-632(2006)
DOI: 10.1126/science.1119133
 https://doi.org/10.1126/science.1119133
https://pubmed.ncbi.nlm.nih.gov/16410488/

Yamashita T, Ninomiya M, Hernandez Acosta P, Garcia-Verdugo JM, Sunabori T, Sakaguchi M, Adachi K, Kojima T, Hirota Y, Kawase T, Araki N, Abe K, Okano H, Sawamoto K.
Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum.
J Neurosci 26:6627-6636 (2006)
DOI: 10.1523/JNEUROSCI.0149-06.2006
 https://doi.org/10.1523/jneurosci.0149-06.2006
https://pubmed.ncbi.nlm.nih.gov/16775151/

Ninomiya M, Yamashita T, Araki N, Okano H, Sawamoto K.
Enhanced neurogenesis in the ischemic striatum following EGF-induced expansion of transit-amplifying cells in the subventricular zone.
Neurosci Lett 403:63-67 (2006)
DOI:10.1016/j.neulet.2006.04.039
https://doi.org/10.1016/j.neulet.2006.04.039
https://pubmed.ncbi.nlm.nih.gov/16701951/

Kaneko N, Okano H, Sawamoto K.
Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb.
Genes Cells 11:1145-1159 (2006)
DOI: 10.1111/j.1365-2443.2006.01010.x
https://doi.org/10.1111/j.1365-2443.2006.01010.x
https://pubmed.ncbi.nlm.nih.gov/16999735/

Yamashima T, Popivanova BK, Guo J, Kotani S, Wakayama T, Iseki S, Sawamoto K, Okano H, Fujii C, Mukaida N, Tonchev AB.
Implication of “Down syndrome cell adhesion molecule” in the hippocampal neurogenesis of ischemic monkeys.
Hippocampus 16:924-935(2006)
DOI:10.1002/hipo.20223
https://doi.org/10.1002/hipo.20223
https://pubmed.ncbi.nlm.nih.gov/16983647/

Toriya M, Tokunaga A, Sawamoto K, Nakao K, Okano H.
Distinct functions of human numb isoforms revealed by misexpression in the neural stem cell lineage in the Drosophila larval brain.
Dev Neurosci 28:142-155(2006)
DOI: 10.1159/000090760
https://doi.org/10.1159/000090760
https://pubmed.ncbi.nlm.nih.gov/16508311/

Tonchev AB, Yamashima T, Sawamoto K, Okano H.
Transcription factor protein expression patterns by neural or neuronal progenitor cells of adult monkey subventricular zone.
Neuroscience 139:1355-1367 (2006)
DOI:10.1016/j.neuroscience.2006.01.053
https://doi.org/10.1016/j.neuroscience.2006.01.053
https://pubmed.ncbi.nlm.nih.gov/16580139/

Sakaguchi M, Shingo T, Shimazaki T, Okano HJ, Shiwa M, Ishibashi S, Oguro H, Ninomiya M, Kadoya T, Horie H, Shibuya A, Mizusawa H, Poirier F, Nakauchi H, Sawamoto K, Okano H.
A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells.
Proc Natl Acad Sci U S A 103:7112-7117(2006)
DOI:10.1073/pnas.0508793103
https://doi.org/10.1073/pnas.0508793103
https://pubmed.ncbi.nlm.nih.gov/16636291/

Miyagi S, Nishimoto M, Saito T, Ninomiya M, Sawamoto K, Okano H, Muramatsu M, Oguro H, Iwama A, Okuda A.
The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon.
J Biol Chem 281:13374-13381 (2006)
DOI:10.1074/jbc.M512669200
https://doi.org/10.1074/jbc.m512669200
https://pubmed.ncbi.nlm.nih.gov/16547000/

2005

Yamashita T, Sawamoto K, Suzuki S, Suzuki N, Adachi K, Kawase T, Mihara M, Ohsugi Y, Abe K, Okano H.
Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons.
J Neurochem 94:459-468(2005)
DOI: 10.1111/j.1471-4159.2005.03227.x
 https://doi.org/10.1111/j.1471-4159.2005.03227.x
https://pubmed.ncbi.nlm.nih.gov/15998296/

Tonchev AB, Yamashima T, Sawamoto K, Okano H.
Enhanced proliferation of progenitor cells in the subventricular zone and limited neuronal production in the striatum and neocortex of adult macaque monkeys after global cerebral ischemia.
J Neurosci Res 81:776-788(2005)
DOI:10.1002/jnr.20604
https://doi.org/10.1002/jnr.20604
https://pubmed.ncbi.nlm.nih.gov/16047371/

Suzuki S, Yamashita T, Tanaka K, Hattori H, Sawamoto K, Okano H, Suzuki N.
Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats.
J Cereb Blood Flow Metab 25:685-693 (2005)
DOI:10.1038/sj.jcbfm.9600061
https://doi.org/10.1038/sj.jcbfm.9600061
https://pubmed.ncbi.nlm.nih.gov/15716858/

Kanuka H, Hiratou T, Igaki T, Kanda H, Kuranaga E, Sawamoto K, Aigaki T, Okano H, Miura M.
Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity.
Biochim Biophys Acta 1726:225-237 (2005)
DOI: 10.1016/j.bbagen.2005.06.020
https://doi.org/10.1016/j.bbagen.2005.06.020
https://pubmed.ncbi.nlm.nih.gov/16243437/

Hirota Y, Sawamoto K, Takahashi K, Ueda R, Okano H.
The transmembrane protein, Tincar, is involved in the development of the compound eye in Drosophila melanogaster.
Dev Genes Evol 215:90-96 (2005)
DOI: 10.1007/s00427-004-0452-y
https://doi.org/10.1007/s00427-004-0452-y
https://pubmed.ncbi.nlm.nih.gov/15654626/

2004

Yoshizaki T, Inaji M, Kouike H, Shimazaki T, Sawamoto K, Ando K, Date I, Kobayashi K, Suhara T, Uchiyama Y, Okano H.
Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells.
Neurosci Lett 363:33-37 (2004)
DOI:10.1016/j.neulet.2004.03.074
https://doi.org/10.1016/j.neulet.2004.03.074
https://pubmed.ncbi.nlm.nih.gov/15157991/

Yamashima T, Tonchev AB, Vachkov IH, Popivanova BK, Seki T, Sawamoto K, Okano H.
Vascular adventitia generates neuronal progenitors in the monkey hippocampus after ischemia.
Hippocampus 14:861-875 (2004)
DOI:10.1002/hipo.20001
https://doi.org/10.1002/hipo.20001
https://pubmed.ncbi.nlm.nih.gov/15382256/

Unezaki S, Nishizawa M, Okuda-Ashitaka E, Masu Y, Mukai M, Kobayashi S, Sawamoto K, Okano H, Ito S.
Characterization of the isoforms of MOVO zinc finger protein, a mouse homologue of Drosophila Ovo, as transcription factors.
Gene 336:47-58(2004)
DOI: 10.1016/j.gene.2004.03.013
 https://doi.org/10.1016/j.gene.2004.03.013
https://pubmed.ncbi.nlm.nih.gov/15225875/

Tokunaga A, Kohyama J, Yoshida T, Nakao K, Sawamoto K, Okano H.
Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain.
J Neurochem 90:142-154(2004)
DOI: 10.1111/j.1471-4159.2004.02470.x
https://doi.org/10.1111/j.1471-4159.2004.02470.x
https://pubmed.ncbi.nlm.nih.gov/15198674/

2002

Uchida M, Hanai S, Uematsu N, Sawamoto K, Okano H, Miwa M, Uchida K.
Overexpression of poly(ADP-ribose) polymerase disrupts organization of cytoskeletal F-actin and tissue polarity in Drosophila.
J Biol Chem 277:6696-6702(2002)
DOI: 10.1074/jbc.M109826200
https://doi.org/10.1074/jbc.m109826200
https://pubmed.ncbi.nlm.nih.gov/11744702/

Ogawa Y, Sawamoto K, Miyata T, Miyao S, Watanabe M, Nakamura M, Bregman BS, Koike M, Uchiyama Y, Toyama Y, Okano H.
Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats.
J Neurosci Res 69:925-933 (2002)
DOI: 10.1002/jnr.10341
https://doi.org/10.1002/jnr.10341
https://pubmed.ncbi.nlm.nih.gov/12205685/

Kuranaga E, Kanuka H, Igaki T, Sawamoto K, Ichijo H, Okano H, Miura M.
Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila.
Nat Cell Biol 4:705-710 (2002)
DOI:10.1038/ncb842
https://doi.org/10.1038/ncb842
https://pubmed.ncbi.nlm.nih.gov/12198495/

Hirota Y, Sawamoto K, Okano H.
tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila.
Mech Dev 119 Suppl 1:S279-283(2002)
DOI: 10.1016/s0925-4773(03)00129-1
https://doi.org/10.1016/s0925-4773(03)00129-1
https://pubmed.ncbi.nlm.nih.gov/14516698/

2001

Uchida M, Hanai S, Uematsu N, Sawamoto K, Okano H, Miwa M, Uchida K.
Genetic and functional analysis of PARP, a DNA strand break-binding enzyme.
Mutat Res 477:89-96 (2001)
DOI:10.1016/s0027-5107(01)00110-5
https://doi.org/10.1016/s0027-5107(01)00110-5
https://pubmed.ncbi.nlm.nih.gov/11376690/

Sawamoto K, Yamamoto A, Kawaguchi A, Yamaguchi M, Mori K, Goldman SA, Okano H.
Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent proteins regulated by stage-specific neural promoters.
J Neurosci Res 65:220-227 (2001)
DOI: 10.1002/jnr.1145
https://doi.org/10.1002/jnr.1145
https://pubmed.ncbi.nlm.nih.gov/11494356/

Sawamoto K, Nakao N, Kobayashi K, Matsushita N, Takahashi H, Kakishita K, Yamamoto A, Yoshizaki T, Terashima T, Murakami F, Itakura T, Okano H.
Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons.
Proc Natl Acad Sci U S A 98:6423-6428(2001)
DOI:10.1073/pnas.111152398
https://doi.org/10.1073/pnas.111152398
https://pubmed.ncbi.nlm.nih.gov/11353855/

Sawamoto K, Nakao N, Kakishita K, Ogawa Y, Toyama Y, Yamamoto A, Yamaguchi M, Mori K, Goldman SA, Itakura T, Okano H.
Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene.
J Neurosci 21:3895-3903(2001)
DOI:10.1523/JNEUROSCI.21-11-03895.2001
https://doi.org/10.1523/jneurosci.21-11-03895.2001
https://pubmed.ncbi.nlm.nih.gov/11356877/

Kawaguchi A, Miyata T, Sawamoto K, Takashita N, Murayama A, Akamatsu W, Ogawa M, Okabe M, Tano Y, Goldman SA, Okano H
Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells.
Mol Cell Neurosci 17:259-273(2001)
DOI:10.1006/mcne.2000.0925
https://doi.org/10.1006/mcne.2000.0925
https://pubmed.ncbi.nlm.nih.gov/11178865/

2000

Taguchi A, Sawamoto K, Okano H.
Mutations modulating the Argos-regulated signaling pathway in Drosophila eye development.
Genetics 154:1639-1648 (2000)
DOI:10.1093/genetics/154.4.1639
https://doi.org/10.1093/genetics/154.4.1639
https://pubmed.ncbi.nlm.nih.gov/10747059/

Tabuchi K, Sawamoto K, Suzuki E, Ozaki K, Sone M, Hama C, Tanifuji-Morimoto T, Yuasa Y, Yoshihara Y, Nose A, Okano H.
GAL4/UAS-WGA system as a powerful tool for tracing Drosophila transsynaptic neural pathways.
J Neurosci Res 59:94-99(2000)
https://pubmed.ncbi.nlm.nih.gov/10658189/

Kaneko Y, Sakakibara S, Imai T, Suzuki A, Nakamura Y, Sawamoto K, Ogawa Y, Toyama Y, Miyata T, Okano H.
Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells.
Dev Neurosci 22:139-153(2000)
DOI:10.1159/000017435
https://doi.org/10.1159/000017435
https://pubmed.ncbi.nlm.nih.gov/10657706/

Jin MH, Sawamoto K, Ito M, Okano H.
The interaction between the Drosophila secreted protein argos and the epidermal growth factor receptor inhibits dimerization of the receptor and binding of secreted spitz to the receptor.
Mol Cell Biol 20:2098-2107 (2000)
DOI:10.1128/MCB.20.6.2098-2107.2000
https://doi.org/10.1128/mcb.20.6.2098-2107.2000
https://pubmed.ncbi.nlm.nih.gov/10688656/

1999

Yoshihara Y, Mizuno T, Nakahira M, Kawasaki M, Watanabe Y, Kagamiyama H, Jishage K, Ueda O, Suzuki H, Tabuchi K, Sawamoto K, Okano H, Noda T, Mori K.
A genetic approach to visualization of multisynaptic neural pathways using plant lectin transgene.
Neuron 22:33-41 (1999)
DOI: 10.1016/s0896-6273(00)80676-5
https://doi.org/10.1016/s0896-6273(00)80676-5
https://pubmed.ncbi.nlm.nih.gov/10027287/

Sawamoto K, Yamada C, Kishida S, Hirota Y, Taguchi A, Kikuchi A, Okano H.
Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development.
Oncogene 18:1967-1974(1999)
DOI:10.1038/sj.onc.1202522
https://doi.org/10.1038/sj.onc.1202522
https://pubmed.ncbi.nlm.nih.gov/10208418/

Sawamoto K, Winge P, Koyama S, Hirota Y, Yamada C, Miyao S, Yoshikawa S, Jin MH, Kikuchi A, Okano H.
The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway.
J Cell Biol 146:361-372(1999)
DOI: 10.1083/jcb.146.2.361
 https://doi.org/10.1083/jcb.146.2.361
https://pubmed.ncbi.nlm.nih.gov/10427090/

Kanuka H, Sawamoto K, Inohara N, Matsuno K, Okano H, Miura M.
Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator.
Mol Cell 4:757-769(1999)
DOI: 10.1016/s1097-2765(00)80386-x
https://doi.org/10.1016/s1097-2765(00)80386-x
https://pubmed.ncbi.nlm.nih.gov/10619023/

Kanuka H, Hisahara S, Sawamoto K, Shoji S, Okano H, Miura M.
Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: implicated mechanisms for caspase activation.
Proc Natl Acad Sci U S A 96:145-150 (1999)
DOI: 10.1073/pnas.96.1.145
https://doi.org/10.1073/pnas.96.1.145
https://pubmed.ncbi.nlm.nih.gov/9874786/

Hirota Y, Okabe M, Imai T, Kurusu M, Yamamoto A, Miyao S, Nakamura M, Sawamoto K, Okano H.
Musashi and seven in absentia downregulate Tramtrack through distinct mechanisms in Drosophila eye development.
Mech Dev 87:93-101 (1999)
DOI: 10.1016/s0925-4773(99)00143-4
https://doi.org/10.1016/s0925-4773(99)00143-4
https://pubmed.ncbi.nlm.nih.gov/10495274/

1998

Sawamoto K, Taguchi A, Hirota Y, Yamada C, Jin MH, Okano H.
Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway.
Cell Death Differ 5:262-70(1998)
DOI: 10.1038/sj.cdd.4400342
https://doi.org/10.1038/sj.cdd.4400342
https://pubmed.ncbi.nlm.nih.gov/10200472/

Saito T, Sawamoto K, Okano H, Anderson DJ, Mikoshiba K.
Mammalian BarH homologue is a potential regulator of neural bHLH genes.
Dev Biol 199:216-225 (1998)
DOI: 10.1006/dbio.1998.8889
https://doi.org/10.1006/dbio.1998.8889
https://pubmed.ncbi.nlm.nih.gov/9698441/

1997

Sawamoto K, Takahashi N.
Modulation of hepatocyte function by changing the cell shape in primary culture.
In Vitro Cell Dev Biol Anim 33:569-574 (1997)
DOI:10.1007/s11626-997-0100-8
https://doi.org/10.1007/s11626-997-0100-8
https://pubmed.ncbi.nlm.nih.gov/9282318/

1996

Sawamoto K, Okabe M, Tanimura T, Mikoshiba K, Nishida Y, Okano H.
The Drosophila secreted protein Argos regulates signal transduction in the Ras/MAPK pathway.
Dev Biol 178:13-22 (1996)
DOI:10.1006/dbio.1996.0194
https://doi.org/10.1006/dbio.1996.0194
https://pubmed.ncbi.nlm.nih.gov/8812105/

Sawamoto K, Okabe M, Tanimura T, Hayashi S, Mikoshiba K, Okano H.
argos Is required for projection of photoreceptor axons during optic lobe development in Drosophila.
Dev Dyn 205:162-171 (1996)
DOI: 10.1002/(SICI)1097-0177(199602)205:2<162::AID-AJA7>3.0.CO;2-G
https://doi.org/10.1002/(sici)1097-0177(199602)205:2%3C162::aid-aja7%3E3.0.co;2-g
https://pubmed.ncbi.nlm.nih.gov/8834476/

Okabe M, Sawamoto K, Okano H.
The function of the Drosophila argos gene product in the development of embryonic chordotonal organs.
Dev Biol 175:37-49 (1996)
DOI:10.1006/dbio.1996.0093
https://doi.org/10.1006/dbio.1996.0093
https://pubmed.ncbi.nlm.nih.gov/8608867/

1995

Sawamoto K, Takahashi N.
Changes in the organelle arrangement in primary cultured hepatocytes following the formation of cytoskeleton.
Int J Tissue React 17:205-210(1995)
https://pubmed.ncbi.nlm.nih.gov/8835631/

1994

Sawamoto K, Okano H, Kobayakawa Y, Hayashi S, Mikoshiba K, Tanimura T.
The function of argos in regulating cell fate decisions during Drosophila eye and wing vein development.
Dev Biol 164:267-276 (1994)
DOI:10.1006/dbio.1994.1197
https://doi.org/10.1006/dbio.1994.1197
https://pubmed.ncbi.nlm.nih.gov/8026629/

Okano H, Yoshikawa S, Suzuki A, Ueno N, Kaizu M, Okabe M, Takahashi T, Matsumoto M, Sawamoto K, Mikoshiba K.
Cloning of a Drosophila melanogaster homologue of the mouse type-I bone morphogenetic proteins-2/-4 receptor: a potential decapentaplegic receptor.
Gene 148:203-209 (1994)
DOI:10.1016/0378-1119(94)90690-4
https://doi.org/10.1016/0378-1119(94)90690-4
https://pubmed.ncbi.nlm.nih.gov/7958946/

1992

Okano H, Hayashi S, Tanimura T, Sawamoto K, Yoshikawa S, Watanabe J, Iwasaki M, Hirose S, Mikoshiba K, Montell C.
Regulation of Drosophila neural development by a putative secreted protein.
Differentiation 52:1-11 (1992)
DOI:10.1111/j.1432-0436.1992.tb00494.x
https://doi.org/10.1111/j.1432-0436.1992.tb00494.x
https://pubmed.ncbi.nlm.nih.gov/1286772/