Selected publications 代表的論文
Matsumoto M, Matsushita K, Hane M, Wen C, Kurematsu C, Ota H, Nguyen HB, Thai TQ, Herranz-Pérez V, Sawada M, Fujimoto K, García-Verdugo JM, Kimura KD, Seki T, Sato C, Ohno N, Sawamoto K. Neuraminidase inhibition promotes the collective migration of neurons and recovery of brain function. EMBO Mol. Med Online ahead of print.(2024)
DOI:10.1038/s44321-024-00073-7
https://doi.org/10.1038/s44321-024-00073-7
https://pubmed.ncbi.nlm.nih.gov/38789599/
Nakajima C, Sawada M, Umeda E, Takagi Y, Nakashima N, Kuboyama K, Kaneko N, Yamamoto S, Nakamura H, Shimada N, Nakamura K, Matsuno K, Uesugi S, Vepřek NA, Küllmer F, Nasufović V, Uchiyama H, Nakada M, Otsuka Y, Ito Y, Herranz-Pérez V, García-Verdugo JM, Ohno N, Arndt HD, Trauner D, Tabata Y, Igarashi M, Sawamoto K. Identification of the growth cone as a probe and driver of neuronal migration in the injured brain. Nat. Commun. 15, 1877 (2024)
DOI:10.1038/s41467-024-45825-8
https://doi.org/10.1038/s41467-024-45825-8
https://pubmed.ncbi.nlm.nih.gov/38461182/
Ohno Y, Nakajima C, Ajioka I, Muraoka T, Yaguchi A, Fujioka T, Akimoto S, Matsuo M, Lotfy A, Nakamura S, Herranz-Pérez V, García-Verdugo JM, Matsukawa N, Kaneko N, Sawamoto K. Amphiphilic peptide-tagged N-cadherin forms radial glial-like fibers that enhance neuronal migration in injured brain and promote sensorimotor recovery. Biomaterials 294:122003 (2023)
DOI:10.1016/j.biomaterials.2023.122003
https://doi.org/10.1016/j.biomaterials.2023.122003
https://pubmed.ncbi.nlm.nih.gov/36736095/
Kurematsu C, Sawada M, Ohmuraya M, Tanaka M, Kuboyama K, Ogino T, Matsumoto M, Oishi H, Inada H, Ishido Y, Sakakibara Y, Nguyen HB, Thai TQ, Kohsaka S, Ohno N, Yamada MK, Asai M, Sokabe M, Nabekura J, Asano K, Tanaka M, Sawamoto K. Synaptic pruning of murine adult-born neurons by microglia depends on phosphatidylserine. J Exp Med 219 (4): e20202304 (2022)
DOI:10.1084/jem.20202304
https://doi.org/10.1084/jem.20202304
https://pubmed.ncbi.nlm.nih.gov/35297954/
Kaneko N, Herranz-Pérez V, Otsuka T, Sano H, Ohno N, Omata T, Nguyen HB, Thai TQ, Nambu A, Kawaguchi Y, García-Verdugo JM, Sawamoto K. New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration. Sci Adv 4: eaav0618 (2018)
DOI: 10.1126/sciadv.aav0618
https://doi.org/10.1126/sciadv.aav0618
http://advances.sciencemag.org/content/4/12/eaav0618
Sawada M, Ohno N, Kawaguchi M, Huang S, Hikita T, Sakurai Y, Nguyen HB, Thai TQ, Ishido Y, Yoshida Y, Nakagawa H, Uemura A, Sawamoto K. PlexinD1 signaling controls morphological changes and migration termination in newborn neurons. EMBO J 37: e97404 (2018)
DOI:10.15252/embj.201797404
http://emboj.embopress.org/cgi/doi/10.15252/embj.201797404
https://pubmed.ncbi.nlm.nih.gov/29348324/
Jinnou H, Sawada M, Kawase K, Kaneko N, Herranz-Pérez V, Miyamoto T, Kawaue T, Miyata T, Tabata Y, Akaike T, García-Verdugo JM, Ajioka I, Saitoh S, Sawamoto K. Radial glial fibers promote neuronal migration and functional recovery after neonatal brain injury. Cell Stem Cell 22: 128-137(2018)
DOI:10.1016/j.stem.2017.11.005
https://doi.org/10.1016/j.stem.2017.11.005
https://pubmed.ncbi.nlm.nih.gov/29276142/
Ota H, Hikita T, Sawada M, Nishioka T, Matsumoto M, Komura M, Ohno A, Kamiya Y, Miyamoto T, Asai N, Enomoto A, Takahashi M, Kaibuchi K, Sobue K, Sawamoto K. Speed control for neuronal migration in the postnatal brain by Gmip-mediated local inactivation of RhoA. Nat Commun 5: 4532 (2014)
DOI:10.1038/ncomms5532
https://doi.org/10.1038/ncomms5532
https://pubmed.ncbi.nlm.nih.gov/25074242/
Kishimoto N, Asakawa K, Madelaine R, Blader P, Kawakami K, Sawamoto K. Interhemispheric asymmetry of olfactory input-dependent neuronal specification in the adult brain. Nat Neurosci 16: 884-888 (2013)
DOI: 10.1038/nn.3409
https://doi.org/10.1038/nn.3409
http://www.ncbi.nlm.nih.gov/pubmed/23685722
Kaneko N, Marin O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K. New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron 67: 213-223 (2010)
DOI:10.1016/j.neuron.2010.06.018
https://doi.org/10.1016/j.neuron.2010.06.018
https://pubmed.ncbi.nlm.nih.gov/20670830/
Sawamoto K, Wichterle H, Gonzalez-Perez O, Cholfin JA, Yamada M, Spassky N, Murcia NS, Garcia-Verdugo JM, Marin O, Rubenstein JL, Tessier-Lavigne M, Okano H, Alvarez-Buylla A. New neurons follow the flow of cerebrospinal fluid in the adult brain. Science 311: 629-632 (2006)
DOI: 10.1126/science.1119133
https://doi.org/10.1126/science.1119133
https://pubmed.ncbi.nlm.nih.gov/16410488/
Sawamoto K, Nakao N, Kobayashi K, Matsushita N, Takahashi H, Kakishita K, Yamamoto A, Yoshizaki T, Terashima T, Murakami F, Itakura T, Okano H. Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proc Natl Acad Sci U S A 98: 6423-6428 (2001)
DOI:10.1073/pnas.111152398
https://doi.org/10.1073/pnas.111152398
https://pubmed.ncbi.nlm.nih.gov/11353855/
Sawamoto K, Winge P, Koyama S, Hirota Y, Yamada C, Miyao S, Yoshikawa S, Jin MH, Kikuchi A, Okano H. The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway. J Cell Biol 146: 361-372 (1999)
DOI: 10.1083/jcb.146.2.361
https://doi.org/10.1083/jcb.146.2.361
https://pubmed.ncbi.nlm.nih.gov/10427090/
